Gene Mb2494
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE AMINOPEPTIDASE N PEPN (LYSYL AMINOPEPTIDASE) (LYS-AP) (ALANINE AMINOPEPTIDASE) |
| Comments | Mb2494, pepN, len: 861 aa. Equivalent to Rv2467,len: 861 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 861 aa overlap). Probable pepN,aminopeptidase N (EC 3.4.11.2), equivalent to Q9CBX9|ML1486 PROBABLE AMINOPEPTIDASE from Mycobacterium leprae (862 aa), FASTA scores: opt: 4751,E(): 0, (83.3% identity in 862 aa overlap). Also highly similar to others e.g. Q11010|AMPN_STRLI|PEPN from Streptomyces lividans (857 aa), FASTA scores: opt: 2839, E(): 1.8e-170, (53.25% identity in 864 aa overlap); Q9L1Z2|PEPN from Streptomyces coelicolor (857 aa), FASTA scores: opt: 2834, E(): 3.8e-170, (53.1% identity in 864 aa overlap); P37896|AMPN_LACDL|PEPN from Lactobacillus delbrueckii (subsp. lactis) (842 aa), FASTA scores: opt: 719, E(): 2.4e-37, (31.65% identity in 439 aa overlap); etc. Contains PS00142 Neutral zinc metallopeptidases,zinc-binding region signature. BELONGS TO PEPTIDASE FAMILY M1 (ZINC METALLOPROTEASE), ALSO KNOWN AS THE PEPN SUBFAMILY. Note that previously known as pepD. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2737149 | 2739734 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2494|pepN
MALPNLTRDQAVERAALITVDSYQIILDVTDGNGAPGERTFRSTTTVVFDALPGADTVIDISAHTVRRASLNDQDLDVSGYDEAAGIPLRGLAQRNVVVVDADCHYSNTGEGLHRFVDPVDGETYLYSQFETADAKRMFACFDQPDLKATFDVRVTAPAHWKVISNGAPLAAANGVHTFATTPRMSTYLVALIAGPYAAWTDTYIDDHGEIPLGIYCRASLAEYMDAERLFTQTKQGFGFYHKHFGLPYAFGKYDQLFVPEFNAGAMENAGAVTFLEDYVFRSKVTRASYERRAETVLHEMAHMWFGDLVTMTWWDDLWLNESFATFASVLCQSEATEFTEAWTTFATVEKSWAYRQDQLPSTHPIAADIPDLAAVEVNFDGITYAKGASVLKQLVAYVGLERFLAGLRDYFRTHAFGNASFDDLLAALEKASGRDLSNWGEQWLKTTGLNTLRPDFEVDAEGRFTRFAVTQSGAAPGAGETRVHRLAVGIYDDDGSKSSGKLVRVHREELDVSGPITNVPALVGVSRGKLILVNDDDLTYCSLRLDERSLQTALDRIADIAEPLPRTLVWSAAWEMTREAELRARDFVSLVSGGVHAETEVGVAQRLLLQAQTALGCYAEPGWARERGWPQFADRLLELAREAEPGSDHQLAYINSLCSSVLSPRHVQTLGALLEGEPAACGLAGLAVDTDLRWRIVTALATAGAIDADGPETPRIDAEVQRDPTAAGKRHAAQARAARPQFVVKDEAFTTVVEDDTLANATGRAMIAGIAAPGQGELLKPFARRYFQAIPGVWARRSSEVAQSVVIGLYPHWDISEQGITAAEEFLSDPEVPPALRRLVLEGQAAVQRSLRARNFDADG
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