Gene Mb2514c in Mycobacterium bovis AF2122/97
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS42a
Gene length621 bp
IdentifierMb2514c
Location 2763566 bp
Protein summary information
Molecular mass22521.6 Da
Isoelectric point12.5462
Protein length206 amino acids
Cross-references
InterProIPR000084
UniProtKB/TrEMBLQ7TYH1
SWISS-MODELA0A1R3Y1D3
General annotation
TypeCDS
FunctionUnknown
ProductPE-PGRS FAMILY PROTEIN [FIRST PART]
CommentsMb2514c, PE_PGRS42a, len: 206 aa. Similar to 5' end of Rv2487c, len: 694 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 136 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of Gly-rich proteins, similar to many e.g. AAK47245|MT2919 PE_PGRS family protein from M. tuberculosis strain CDC1515 (663 aa), FASTA scores: opt: 2317, E(): 2.3e-84, (58.35% identity in 622 aa overlap); etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PE_PGRS42 exists as a single gene. In Mycobacterium bovis, 2 frameshifts, the first due to a single base insertion (*-c) and the second due to a single base deletion (g-*) splits PE_PGRS42 into 3 parts,PE_PGRS42a and PE_PGRS42b and PE_PGRS42d.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27635662764186-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2514c|PE_PGRS42a
MSLVIATPQLLATAALDLASIGSQVSAANAAAAMPTTEVVAAAADEVSAAIAGLFGAHARQYQALSVQVAAFHEQFVQALTAAAGRYASTEAAVERSLLGAVNAPTEALLGRPLIGNGADGTAPGQPGAAGGLLFGQRWQRRGWRVRSNRRQRRRGRVDRQRRQRRGRWYRRGRRCRWERGVVVGQRRQRRCRRHQRGRRHRGCGR
Bibliography
No article yet recorded