Gene Mb2518c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PE-PGRS FAMILY PROTEIN [FIRST PART] |
| Comments | Mb2518c, PE_PGRS43a, len: 509 aa. Similar to 5' end of Rv2490c, len: 1660 aa, from Mycobacterium tuberculosis strain H37Rv, (98.0% identity in 444 aa overlap). Member of the Mycobacterium tuberculosis PE family,PGRS-subfamily of Gly-rich proteins, similar to many e.g. AAK47971|MT3612.1 PE_PGRS family protein from Mycobacterium tuberculosis strain CDC1551 (1715 aa), FASTA scores: opt: 5161, E(): 1.5e-187, (51.7% identity in 1752 aa overlap); etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PE_PGRS43 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 8 bp insertion (*-gggggggg) splits PE_PGRS43 into 2 parts, PE_PGRS43a and PE_PGRS43b. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2771504 | 2773033 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2518c|PE_PGRS43a
MSYVIATPEMMATAAFDLARIGSQVSAASAVAAMPTTEVVAAGADEVSAGIAALFSAHAQEYQALSAQAAAFHDQFVHTLTAAARWYTATEIANAAAMRVVLGAVNAPTQTLLGRPLIGDGAHGTAPGQPGGAGGLLFGNGGNGAAGAVGQVGGAGGAAGLFGIGGAGGAGGAGAPGGTGGTGGWLAGGGGVGGMGGAGGGAGGAGGNAGLFGNGGAGGAGGAGGGAGGAGGNAGWFGHGGAGGVGGVGAAGANGATPGQDGAAGVAGSDDGAGGDGLAGSDGGDGGAGGVGGNGGRGGWLLGNGGAGGVGGVGGAGGAGAAGGAGGAGATGINGPAGISAAGGDGGAGGNGGAGGNGGVGGAGGAGGSAGLLGYVGRAGDGGAGGGGGLGGAPGDGGAGGNGGSWLAAGDGGAGGHGGDPGLGGAGGAGGGGGRRAAPVLARGPMVWRPATTGRSAAATAAKVAMAPTHRSPAVMAVTAVPVATAGWSVTVGPAVMAVTEPRVPAMPI
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