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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ACYL-COA DEHYDROGENASE FADE19 (MMGC)
CommentsMb2528c, fadE19, len: 394 aa. Equivalent to Rv2500c, len: 394 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 394 aa overlap). Possible fadE19 (alternate gene name: mmgC), acyl-CoA dehydrogenase (EC 1.3.99.-), similar to many e.g. Q9XCG6|ACDH from Streptomyces coelicolor (386 aa), FASTA scores: opt: 1714, E(): 1.1e-98, (69.45% identity in 383 aa overlap); Q9XCG5|ACDH from Streptomyces avermitilis (386 aa), FASTA scores: opt: 1713, E(): 1.3e-98, (70.0% identity in 383 aa overlap); Q9L7W5|FENK from Bacillus subtilis (370 aa), FASTA scores: opt: 1094, E(): 2.3e-60,(48.4% identity in 372 aa overlap); etc. Contains PS00072 Acyl-CoA dehydrogenases signature 1, PS00073 Acyl-CoA dehydrogenases signature 2. BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27805242781708-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2528c|fadE19
MTTTTTTISGGILPKEYQDLRDTVADFARTVVAPVSAKHDAEHSFPYEIVAKMGEMGLFGLPFPEEYGGMGGDYFALSLVLEELGKVDQSVAITLEAAVGLGAMPIYRFGTEEQKQKWLPDLTSGRALAGFGLTEPGAGSDAGSTRTTARLEGDEWIINGSKQFITNSGTDITSLVTVTAVTGTTGTAADAKKEISTIIVPSGTPGFTVEPVYNKVGWNASDTHPLTFADARVPRENLLGARGSGYANFLSILDEGRIAIAALATGAAQGCVDESVKYANQRQSFGQPIGAYQAIGFKIARMEARAHVARTAYYDAAAKMLAGKPFKKEAAIAKMISSEAAMDNSRDATQIHGGYGFMNEYPVARHYRDSKVLEIGEGTTEVQLMLIARSLGLQ
      
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