Gene Mb2530c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameaccD1
Gene length1590 bp
IdentifierMb2530c
Location 2783682 bp
Protein summary information
Molecular mass56773.8 Da
Isoelectric point6.5135
Protein length529 amino acids
Cross-references
InterProIPR000022, IPR011762, IPR011763
UniProtKB/TrEMBLQ7TYF6
SWISS-MODELA0A1R3Y277
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACETYL-/PROPIONYL-COA CARBOXYLASE (BETA SUBUNIT) ACCD1
CommentsMb2530c, accD1, len: 529 aa. Equivalent to Rv2502c,len: 529 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 529 aa overlap). Probable accD1,acetyl-/propionyl-CoA carboxylase (beta subunit) (EC 6.4.1.-), similar, but with N-terminus shorter, to Q9L077|ACCD1 from Streptomyces coelicolor (538 aa), FASTA scores: opt: 2747, E(): 1.9e-159, (77.9% identity in 516 aa overlap). Also similar to others e.g. AAK24141 CC2170 from Caulobacter crescentus (530 aa), FASTA scores: opt: 2413, E(): 3.8e-139, (69.4% identity in 529 aa overlap); BAB54131|MLL7731 from Rhizobium loti (537 aa), FASTA scores: opt: 2399, E(): 2.7e-138, (67.4% identity in 527 aa overlap); etc. COULD BELONG TO THE ACCD/PCCB FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27836822785271-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2530c|accD1
MTTPSIAIAPSFADEHRRLVAELNNKLAAAALGGNERARKRHVSRGKLLPRERVDRLLDPGSPFLELAPLAAGGMYSDESPGAGIITGIGRVSGRQCVIVANDATVKGGTYYPMTVKKHLRAQEVALQNMLPCIYLVDSGGAFLPRQDEVFPDREHFGRIFYNQATMSAKGIPQVAAVLGSCTAGGAYVPAMSDEAVIVREQGTIFLGGPPLVKAATGEIVSAEELGGGDLHSRTSGVTDHLADDDEDALRIVRAIADTFGPCEPAQWDVRRSVEPKYPQAELYDVVPPDPRVPYDVHEVVVRIVDGSEFSEFKAKYGKTLVTAFARVHGHPVGIVANNGVLLSESALKGAHFIELCDKRKIPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYEDQGNPYYSTARLWDDGIIDPADTRTVVGLALSLCAHAPLDQVGYGVFRM
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