Gene Mb2547c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | probable l,d-transpeptidase ldtb |
| Comments | Mb2547c, lppS, len: 408 aa. Equivalent to Rv2518c,len: 408 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 408 aa overlap). Probable lppS,conserved lipoprotein, highly similar to O07707|MLCL383.3 HYPOTHETICAL 43.6 KDA PROTEIN from Mycobacterium leprae (407 aa), FASTA scores: opt: 2300, E(): 1.2e-130, (82.5% identity in 406 aa overlap); Q9CCU5|LPPS|ML0426 PUTATIVE SECRETED PROTEIN from Mycobacterium leprae (404 aa), FASTA scores: opt: 2279, E(): 2.3e-129, (82.4% identity in 403 aa overlap); and Q9CB49|ML2446 POSSIBLE LIPOPROTEIN from Mycobacterium leprae (441 aa), FASTA scores: opt: 736,E(): 8.4e-37, (35.6% identity in 399 aa overlap). Also similar to other proteins from several organisms e.g. Q9X811|SC6G10.26c PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (424 aa), FASTA scores: opt: 867,E(): 1.1e-44, (32.25% identity in 403 aa overlap); Q9L1E8|SC3D11.14 PUTATIVE LIPOPROTEIN from Streptomyces coelicolor (416 aa), FASTA scores: opt: 737, E(): 7e-37,(32.95% identity in 413 aa overlap); Q9KYV1|SCE22.11 PUTATIVE LIPOPROTEIN from Streptomyces coelicolor (407 aa), FASTA scores: opt: 721, E(): 6.2e-36, (33.5% identity in 400 aa overlap). And similar to several hypothetical mycobacterial proteins e.g. Q11149|Y483_MYCTU|Rv0483|MT0501|MTCY20G9.09 (451 aa),FASTA scores: opt: 763, E(): 2.1e-38, (34.85% identity in 402 aa overlap). Has very long signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2800906 | 2802132 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2547c|ldtb
MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA
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