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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productprobable cytoplasmic peptidase pepq
CommentsMb2564c, pepQ, len: 372 aa. Equivalent to Rv2535c,len: 372 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 372 aa overlap). Probable pepQ,cytoplasmic peptidase (EC 3.4.-.-), equivalent to Q9CCS1|PEPQ|ML0521 PUTATIVE CYTOPLASMIC PEPTIDASE from Mycobacterium leprae (376 aa), FASTA scores: opt: 1954,E(): 1.1e-105, (82.7% identity in 376 aa overlap). Also similar to other peptidases e.g. P54518|YQHT_BACSU PUTATIVE PEPTIDASE (BELONGS TO PEPTIDASE FAMILY M24B) from Bacillus subtilis (353 aa), FASTA scores: opt: 808, E(): 1.6e-39, (39.65% identity in 368 aa overlap); Q9KXQ8|SC9C5.16c PUTATIVE PEPTIDASE from Streptomyces coelicolor (368 aa), FASTA scores: opt: 803, E(): 3.2e-39,(43.15% identity in 380 aa overlap); Q9K950|BH2800 XAA-PRO DIPEPTIDASE from Bacillus halodurans (355 aa), FASTA scores: opt: 801, E(): 4.1e-39, (39.45% identity in 365 aa overlap); etc. Note that second part of protein is similar to second part of MTCY49.29c|Rv2089c|MT2150|MTCY49.29c PROBABLE DIPEPTIDASE (EC 3.4.13.-; BELONGS TO PEPTIDASE FAMILY M24B) from Mycobacterium tuberculosis (375 aa) (33.9% identity in 354 aa overlap) BLAST RESULTS: Score: 142 bits (359), E: 4e-33, Identities: 86/224 (38%),Positives: 119/224 (52%), Gaps: 4/224 (1%). COULD BE BELONG TO PEPTIDASE FAMILY M24B.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28260972827215-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2564c|pepQ
MTHSQRRDKLKAQIAASGLDAMLISDLINVRYLSGFSGSNGALLVFADERDAVLATDGRYRTQAASQAPDLEVAIERAVGRYLAGRAGEAGVGKLGFESHVVTVDGLDALAGALEGKNTELVRASGTVESLREVKDAGELALLRLACEAADAALTDLVARGGLRPGRTERQVSRELEALMLDHGADAVSFETIVAAGANSAIPHHRPTDAVLQVGDFVKIDFGALVAGYHSDMTRTFVLGKAADWQLEIYQLVAEAQQAGRQALLPGAELRGVDAAARQLIADAGYGEHFGHGLGHGVGLQIHEAPGIGVTSAGTLLAGSVVTVEPGVYLPGRGGVRIEDTLVVAGGTPKMPETAGQTPELLTRFPKELAIL
      
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