Gene Mb2569c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE CHORISMATE SYNTHASE AROF (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE PHOSPHOLYASE) |
| Comments | Mb2569c, aroF, len: 401 aa. Equivalent to Rv2540c,len: 401 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 401 aa overlap). Probable aroF (alternate gene name: aroC), chorismate synthase (EC 4.2.3.5), equivalent to Q9CCS6|AROF|ML0516 PUTATIVE CHORISMATE SYNTHASE from Mycobacterium leprae (407 aa),FASTA scores: opt: 2278, E(): 6.2e-123, (88.05% identity in 401 aa overlap). Also highly similar to many e.g. Q9X5D0|AROC_CORGL from Corynebacterium glutamicum (Brevibacterium flavum) (410 aa), FASTA scores: opt: 1811,E(): 3e-96, (70.3% identity in 397 aa overlap); Q9KXQ4|AROC_STRCO|AROF|SC9C5.20c from Streptomyces coelicolor (394 aa), FASTA scores: opt: 1710, E(): 1.7e-90, (67.0% identity in 385 aa overlap); Q9KCB7|AROC_BACHD|AROF|BH1656 from Bacillus halodurans (390 aa), FASTA scores: opt: 1196, E(): 3.9e-61, (48.7% identity in 386 aa overlap); etc. Contains PS00788 Chorismate synthase signature 2. BELONGS TO THE CHORISMATE SYNTHASE FAMILY. COFACTOR: REDUCED FLAVIN. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2830004 | 2831209 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2569c|aroF
MLRWITAGESHGRALVAVVEGMVAGVHVTSADIADQLARRRLGYGRGARMTFERDAVTVLSGIRHGSTLGGPIAIEIGNTEWPKWETVMAADPVDPAELADVARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTVARAFLRQALGVEVLSHVISIGASAPYEGPPPRAEDLPAIDASPVRAYDKAAEADMIAQIEAAKKDGDTLGGVVEAVALGLPVGLGSFTSGDHRLDSQLAAAVMGIQAIKGVEIGDGFQTARRRGSRAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGDEAVAIHQRSDVCAVPAAGVVVETMVALVLARAALEKFGGDSLAETQRNIAAYQRSVADREAPAARVSG
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