Gene Mb2589c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2589c
Gene length1359 bp
IdentifierMb2589c
Location 2846023 bp
Protein summary information
Molecular mass47557.2 Da
Isoelectric point6.5212
Protein length452 amino acids
Orthologues
M. tuberculosisRv2559c
Cross-references
InterProIPR003593, IPR003959, IPR008921, IPR021886, IPR027417
UniProtKB/TrEMBLQ7TYB0
SWISS-MODELA0A1R3Y1T6
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL ALANINE LEUCINE VALINE RICH PROTEIN
CommentsMb2589c, -, len: 452 aa. Equivalent to Rv2559c,len: 452 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 452 aa overlap). Conserved hypothetical ala-, leu-, val-rich protein, equivalent to Q9CCT1|ML0510 HYPOTHETICAL PROTEIN from Mycobacterium leprae (473 aa),FASTA scores: opt: 2411, E(): 3.9e-121, (83.4% identity in 452 aa overlap); O69490|O69490 HYPOTHETICAL 47.1 KDA PROTEIN from Mycobacterium leprae (447 aa), FASTA scores: opt: 2406, E(): 6.9e-121, (83.95% identity in 448 aa overlap). Also highly similar to Q9KXP4|SC9C5.30c CONSERVED ATP/GTP BINDING PROTEIN from Streptomyces coelicolor (451 aa), FASTA scores: opt: 1742, E(): 1.5e-85, (64.4% identity in 430 aa overlap); Q9RT67|DR1898 CONSERVED HYPOTHETICAL PROTEIN from Deinococcus radiodurans (434 aa), FASTA scores: opt: 1147, E(): 6.6e-54, (46.0% identity in 415 aa overlap); P45262|YCAJ_HAEIN|HI1590 HYPOTHETICAL PROTEIN from Haemophilus influenzae (446 aa), FASTA scores: opt: 1140,E(): 1.6e-53, (42.5% identity in 428 aa overlap); etc. Also similar to Q50629|MTCY227.09|RUVB|Rv2592c|MT2669|MTCY227.09 HOLLIDAY JUNCTION DNA HELICASE from Mycobacterium tuberculosis (344 aa), (30.1% identity in 296 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28460232847381-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2589c|Mb2589c
MPEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPPGSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHGEQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSLILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGELVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADPSALQVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELVDVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG
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