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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL ALANINE LEUCINE VALINE RICH PROTEIN
CommentsMb2589c, -, len: 452 aa. Equivalent to Rv2559c,len: 452 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 452 aa overlap). Conserved hypothetical ala-, leu-, val-rich protein, equivalent to Q9CCT1|ML0510 HYPOTHETICAL PROTEIN from Mycobacterium leprae (473 aa),FASTA scores: opt: 2411, E(): 3.9e-121, (83.4% identity in 452 aa overlap); O69490|O69490 HYPOTHETICAL 47.1 KDA PROTEIN from Mycobacterium leprae (447 aa), FASTA scores: opt: 2406, E(): 6.9e-121, (83.95% identity in 448 aa overlap). Also highly similar to Q9KXP4|SC9C5.30c CONSERVED ATP/GTP BINDING PROTEIN from Streptomyces coelicolor (451 aa), FASTA scores: opt: 1742, E(): 1.5e-85, (64.4% identity in 430 aa overlap); Q9RT67|DR1898 CONSERVED HYPOTHETICAL PROTEIN from Deinococcus radiodurans (434 aa), FASTA scores: opt: 1147, E(): 6.6e-54, (46.0% identity in 415 aa overlap); P45262|YCAJ_HAEIN|HI1590 HYPOTHETICAL PROTEIN from Haemophilus influenzae (446 aa), FASTA scores: opt: 1140,E(): 1.6e-53, (42.5% identity in 428 aa overlap); etc. Also similar to Q50629|MTCY227.09|RUVB|Rv2592c|MT2669|MTCY227.09 HOLLIDAY JUNCTION DNA HELICASE from Mycobacterium tuberculosis (344 aa), (30.1% identity in 296 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28460232847381-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2589c|Mb2589c
MPEAVSDGLFDVPGVPMTSGHDLGASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPPGSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALLHGEQTVLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSLILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARRALTALEVAAEAAQAAGELVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADPSALQVAVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAGKAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELVDVDYYRPTGRGGEREIAGRLDRLRAIIRKKRG
      
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