Gene Mb2603 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2603
Gene length831 bp
IdentifierMb2603
Location 2865401 bp
Protein summary information
Molecular mass29411.8 Da
Isoelectric point7.0879
Protein length276 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_002740
M. tuberculosis H37RvRv2573
Cross-references
UniProtKB/TrEMBLX2BKU7
SWISS-MODELA0A1R3Y1L0
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb2603, -, len: 275 aa. Equivalent to 2-dehydropantoate 2-reductase from Mycobacterium tuberculosis strain CDC1551 (100% identity with 274 aa overlap). Conserved hypothetical protein, similar to various proteins e.g. Rv2573, len: 246 aa, from Mycobacterium tuberculosis strain H37Rv, Q9ABG6|CC0261 HYPOTHETICAL PROTEIN from Caulobacter crescentus (290 aa),Q99R37|SA2393 HYPOTHETICAL PROTEIN (similar to 2-dehydropantoate 2-reductase) from Staphylococcus aureus subsp. aureus N315 (286 aa), Q9KPQ9|VC2307 2-DEHYDROPANTOATE 2-REDUCTASE from Vibrio cholerae (296 aa). PArt of the Ketopantoate reductase PanE/ApbA superfamily. Mb2603 transcript and transcriptional start site identified in Mycobacterium bovis strain AF2122/97 grown under exponential conditions.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28654012866231+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2603|Mb2603
MLHKAGYSPLLCGHTPRAGIELRRDGADPIVVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQPHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAAASDGPG
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