Gene Mb2613
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B PPIB (CYCLOPHILIN) (PPIASE) (ROTAMASE) (PEPTIDYLPROLYL ISOMERASE) |
| Comments | Mb2613, ppiB, len: 308 aa. Equivalent to Rv2582,len: 308 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 308 aa overlap). Probable ppiB (alternate gene name: ppi), cyclophilin (peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8), equivalent to P46697|PPIB_MYCLE|PPI|ML0492|MLCB1259.10c|B1177_F3_97 PROBABLE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B from Mycobacterium leprae (295 aa), FASTA scores: opt: 1423,E(): 1.3e-66, (72.2% identity in 295 aa overlap). Aldo similar to others e.g. Q9KJG8|PPIB PEPTIDYL-PROLYL CIS-TRANS ISOMERASE from Streptomyces lividans (277 aa),FASTA scores: opt: 485, E(): 3.2e-18, (38.35% identity in 292 aa overlap); Q9KXP0|SC9C5.34 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE from Streptomyces coelicolor (277 aa), FASTA scores: opt: 483, E(): 4.1e-18, (38.35% identity in 292 aa overlap); Q9RT72|DR1893 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE from Deinococcus radiodurans (350 aa), FASTA scores: opt: 296, E(): 2.2e-08, (29.0% identity in 276 aa overlap); etc. BELONGS TO THE CYCLOPHILIN-TYPE PPIASE FAMILY. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2874262 | 2875188 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2613|ppiB
MGHLTPVAAPRLACAFVPTNAQRRATAKRKLERQLERRAKQAKRRRILTIVGGSLAAVAVIVAVVFTVVVNKDDHQSTTSATPTDSASTSPPQAATAPPLPPFKPSANLGANCQYPPSPDKAVKPVKLPRTGKVPTDPAQVSVSMVTNQGNIGLMLANNESPCTVNSFVSLAQQGFFKGTTCHRLTTSPMLAVLQCGDPKGDGTGGPGYQFANEYPTDQYSANDPKLNEPVIYPRGTLAMANAGPNTNSSQFFMVYRDSKLPPQYTVFGTIQADGLTTLDKIAKAGVAGGGEDGKPATEVTITSVLLD
Bibliography
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