Gene Mb2618c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | probable protein-export membrane protein secd |
| Comments | Mb2618c, secD, len: 573 aa. Equivalent to Rv2587c,len: 573 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 573 aa overlap).Probable secD,protein-export membrane protein (integral membrane protein), equivalent to P38387|SECD_MYCLE|ML0487|MLCB1259.05|B1177_C1_164 PROTEIN-EXPORT MEMBRANE PROTEIN from Mycobacterium leprae (571 aa), FASTA scores: opt: 2948, E(): 2.6e-97, (80.6% identity in 583 aa overlap). Also similar to others e.g. Q9AE07|SECD from Corynebacterium glutamicum (Brevibacterium flavum) (637 aa), FASTA scores: opt: 1023,E(): 1.9e-29, (44.95% identity in 596 aa overlap); Q53955|SECD_STRCO from Streptomyces coelicolor (570 aa),FASTA scores: opt: 864, E(): 7.2e-24, (38.0% identity in 584 aa overlap); O33517|SECD_RHOCA from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (554 aa), FASTA scores: opt: 551, E(): 7.6e-13, (32.25% identity in 304 aa overlap); etc. Equivalent to AAK46977 from Mycobacterium tuberculosis strain CDC1551 (554 aa) but longer 19 aa. BELONGS TO THE SECD/SECF FAMILY, SECD FAMILY. PART OF THE PROKARYOTIC PROTEIN TRANSLOCATION APPARATUS WHICH COMPRISE SECA|Rv3240c, SECD, SECE|Rv0638, SECF|Rv2586c, SECG|Rv1440 AND SECY|Rv0732. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2881463 | 2883184 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2618c|secD
MASSSAPVHPARYLSVFLVMLIGIYLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQIISARVNGLGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRPVLNSMPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPASPQPGAQPRPYPQDPAPSPNPTSPASPPPAPPAEAPATDPRKDLAERIAQEKKLRQSTNQYMQMVALQFQATRCESDDILAGNDDPKLPLVTCSTDHKTAYLLAPSIISGDQIQNATSGMDQRGIGYVVDLQFKGPAANIWADYTAAHIGTQTAFTLDSQVVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVYSLLYYRVLGLLTALSLVASGSMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRSFRSAVPRGWARARKTIVSGSAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSSLLAKPAYNGLGAVQQVARERRAMARTGRG
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