Gene Mb2623c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE HOLLIDAY JUNCTION DNA HELICASE RUVB |
| Comments | Mb2623c, ruvB, len: 344 aa. Equivalent to Rv2592c,len: 344 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 344 aa overlap). Probable ruvB,Holliday junction binding protein (EC 3.6.1.-) (see first citation below), equivalent to P40833|RUVB_MYCLE|ML0483|B1177_C3_227 HOLLIDAY JUNCTION DNA HELICASE from Mycobacterium leprae (349 aa), FASTA scores: opt: 2059, E(): 2.1e-106, (94.45% identity in 342 aa overlap). Also highly similar to others e.g. Q9AE09|RUVB from Corynebacterium glutamicum (Brevibacterium flavum) (363 aa), FASTA scores: opt: 1651,E(): 6.5e-84, (75.6% identity in 332 aa overlap); Q9L291|RUVB from Streptomyces coelicolor (357 aa), FASTA scores: opt: 1530, E(): 3e-77, (68.2% identity in 343 aa overlap); P08577|RUVB_ECOLI|B1860|Z2912|ECS2570 from Escherichia coli strains K12 and O157:H7 (336 aa), FASTA scores: opt: 1284, E(): 1e-63, (55.45% identity in 330 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE RUVB FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2890656 | 2891690 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2623c|ruvB
MTERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRVATALAWTHLGMTPPVGASQPGLFE
Bibliography
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