Gene Mb2691 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2691
Gene length1587 bp
IdentifierMb2691
Location 2944161 bp
Protein summary information
Molecular mass53993.7 Da
Isoelectric point4.6044
Protein length528 amino acids
Orthologs
M. tuberculosis H37RvRv2672
M. tuberculosis MTBC0mtbc0_002846
Cross-references
InterProIPR013595
UniProtKB/TrEMBLQ7TY52
SWISS-MODELA0A1R3Y1V3
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE SECRETED PROTEASE
CommentsMb2691, -, len: 528 aa. Equivalent to Rv2672, len: 528 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 528 aa overlap). Possible secreted protease (EC 3.4.-.-), equivalent to O05685|MLC1351.24|ML1339 PUTATIVE SECRETED PROTEASE from Mycobacterium leprae (525 aa), FASTA scores: opt: 2722,E(): 9.4e-140, (74.45% identity in 528 aa overlap). Also similar to several exported proteinases from Streptomyces and Mycobacteria e.g. Q54399|SLPE PROTEINASE from Streptomyces lividans (513 aa), FASTA scores: opt: 429,E(): 6.8e-16, (26.2% identity in 538 aa overlap); Q9FCK9|2SC3B6.03c PEPTIDASE from Streptomyces coelicolor (513 aa), FASTA scores: opt: 421, E(): 1.8e-15, (26.45% identity in 541 aa overlap); Q10508|YM23_MYCTU from Mycobacterium tuberculosis (520 aa), FASTA scores: opt: 349, E(): 1.4e-11, (26.6% identity in 523 aa overlap); etc. Equivalent to AAK47061 from Mycobacterium tuberculosis strain CDC1551 (518 aa) but longer 10 aa.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29441612945747+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2691|Mb2691
MATVVGMSRPMTSTAMLVALTCSATVLAACVPAFGADPRFATYSGAGPQGAATTTPPPAGPPPLAAPKNDLSWHDCTSRVYSNAGIPAAPGVKLECASYDTDLDPLVGGSTAVSIGVVRARSNQTPSDAGPLVFTTGSDLPSSTQLPVWLAHAGIDVLRSHPIVAVDRRGMGMSSPIDCRDHFDRDEMRDQAQFQAGDDPVANLSDISNTATTDCTDAIAPGESAYDNTHAASDIERLRKLWDVPALAFVGIGNGTQVALAYAASRPDNVARLILDSPIALGVSAEAAAEQQVQGQQAALDAFAAQCVAVNCALGSDPKGAVSALLSAARSGDGPGGASVAAVANAVATALGFPDSGRVDSTTKLADALAAARSGDMNLLSALINRADTTRDTDGQFISSCSDAVNRPTPDRVRELVVAWGKLYPQFGAVAALNLVKCVHWPSSSPPQPPKDLKVDVLLLGVQNDPIVGNEGVAATAATAINANAASKRVMWQGIGHGASIYSSCAVPPLVAYLDTGKLPDTDTYCPA
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