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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb2694c, -, len: 250 aa. Equivalent to Rv2675c,len: 250 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 250 aa overlap). Conserved hypothetical protein. C-terminus highly similar to Q50010|U1764Z from Mycobacterium leprae (69 aa), FASTA scores: opt: 284, E(): 4.6e-11, (68.25% identity in 63 aa overlap). Shows some similarity with Q9P3V6|SPAC1348.04 (alias Q9P3E7|Q9P7U5) HYPOTHETICAL 16.6 KDA PROTEIN from Schizosaccharomyces pombe (Fission yeast) (145 aa), FASTA scores: opt: 203, E(): 9.5e-06, (33.05% identity in 118 aa overlap); Q9ZSZ7|BMCT METHYL CHLORIDE TRANSFERASE from Batis maritima (230 aa), FASTA scores: opt: 197, E(): 3.3e-05, (28.85% identity in 156 aa overlap); P72459|STSG METHYLTRANSFERASE from Streptomyces griseus (253 aa),FASTA scores: opt: 194, E(): 5.5e-05, (24.45% identity in 229 aa overlap); etc. Also similar to various proteins from Mycobacterium tuberculosis e.g. P71805|Rv1377c|MTCY02B12.11c HYPOTHETICAL 22.8 KDA PROTEIN (212 aa), FASTA scores: opt: 431, E(): 8.3e-20, (39.1% identity in 197 aa overlap); O06426|Rv0560c|MTCY25D10.39c HYPOTHETICAL 25.9 KDA PROTEIN (241 aa), FASTA scores: opt: 379, E(): 1.6e-16, (35.95% identity in 178 aa overlap); O69667|Rv3699|MTV025.047 PUTATIVE METHYLTRANSFERASE (233 aa), FASTA scores: opt: 297, E(): 2e-11, (30.55% identity in 193 aa overlap); etc.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29477182948470-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2694c|Mb2694c
MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATRVD
      
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