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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACYL-CoA DEHYDROGENASE FADE20
CommentsMb2743c, fadE20, len: 386 aa. Equivalent to Rv2724c, len: 386 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 386 aa overlap). Probable fadE20, acyl-CoA dehydrogenase (EC 1.3.99.-), highly similar to many e.g. Q9X7Y2|SC6A5.36 from Streptomyces coelicolor (382 aa), FASTA scores: opt: 1583, E(): 6.9e-94, (62.7% identity in 378 aa overlap); Q9HVY0|PA4435 from Pseudomonas aeruginosa (381 aa), FASTA scores: opt: 1468, E(): 1.6e-86, (57.65% identity in 380 aa overlap); Q9ABZ1|CC0079 from Caulobacter crescentus (391 aa), FASTA scores: opt: 1298, E(): 1.2e-75, (51.9% identity in 391 aa overlap); etc. Also similar to many other Mycobacterium tuberculosis proteins e.g. O06164|FADE19|Rv2500c|MTCY07A7.06c ACYL-CoA DEHYDROGENASE (394 aa) (34.3% identity in 382 aa overlap). Contains acyl-CoA dehydrogenases signature 2 (PS00073). BELONGS TO THE ACYL-CoA DEHYDROGENASES FAMILY.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29927672993927-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2743c|fadE20
MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELATEATVVRIMVDEFIKLHLAGKLTAEQAAMAKWYATEKQVYLNDRCLQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
      
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