Gene Mb2765c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene name35kd_ag
Gene length813 bp
IdentifierMb2765c
Location 3013825 bp
Protein summary information
Molecular mass29257.9 Da
Isoelectric point5.4384
Protein length270 amino acids
Orthologs
M. tuberculosis H37RvRv2744c
M. tuberculosis MTBC0mtbc0_002921
Cross-references
InterProIPR007157
UniProtKB/TrEMBLQ7TXZ5
SWISS-MODELA0A1R3Y211
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED 35 KDA ALANINE RICH PROTEIN
CommentsMb2765c, 35kd_ag, len: 270 aa. Equivalent to Rv2744c, len: 270 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 270 aa overlap). 35kd_ag,conserved ala-rich protein 35-kd antigen (see citation below). N-terminal part is equivalent to Q49840|MLCB33.06c|B2235_C2_187 HYPOTHETICAL PROTEIN from Mycobacterium leprae (167 aa), FASTA scores: opt: 789,E(): 3.4e-35, (85.05% identity in 147 aa overlap); and C-terminal part equivalent to Q49845|MLCB33.05c|B2235_C3_214 HYPOTHETICAL PROTEIN from Mycobacterium leprae (114 aa), FASTA scores: opt: 465,E(): 3.6e-18, (65.8% identity in 114 aa overlap); note that these two proteins from Mycobacterium leprae are adjacent. Shows some similarity with Q55707||Y617_SYNY3|SLL0617 HYPOTHETICAL 28.9 KDA PROTEIN from Synechocystis sp. strain PCC 6803 (267 aa), FASTA scores: opt: 155, E(): 0.19, (23.4% identity in 252 aa overlap); and C-terminus of Q9L4N1|EMM M PROTEIN from Streptococcus equisimilis (592 aa), FASTA scores: opt: 165, E(): 0.11, (23.45% identity in 260 aa overlap). C-terminus also similar to AAK45945|MT1676 CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis strain CDC1551 (85 aa), FASTA scores: opt: 159, E(): 0.047, (50.9% identity in 55 aa overlap).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30138253014637-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2765c|35kd_ag
MANPFVKAWKYLMALFSSKIDEHADPKVQIQQAIEEAQRTHQALTQQAAQVIGNQRQLEMRLNRQLADIEKLQVNVRQALTLADQATAAGDAAKATEYNNAAEAFAAQLVTAEQSVEDLKTLHDQALSAAAQAKKAVERNAMVLQQKIAERTQLLSQLEQAKMQEQVSASLRSMSELAAPGNTPSLDEVRDKIERRYANAIGSAELAESSVQGRMLEVEQAGIQMAGHSRLEQIRASMRGEALPAGGTTATPRPATETSGGAIAEQPYGQ
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