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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TYPE I RESTRICTION/MODIFICATION SYSTEM SPECIFICITY DETERMINANT HSDS (S PROTEIN)
CommentsMb2782c, hsdS, len: 364 aa. Equivalent to Rv2761c,len: 364 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 364 aa overlap). Possible hsdS, type I restriction/modification system specificity determinant (S protein), similar in part to other hsdS protein (S PROTEINS) e.g. Q9P9X9|XF2741 from Xylella fastidiosa (412 aa), FASTA scores: opt: 252, E(): 7.4e-09, (24.95% identity in 401 aa overlap); N-terminus of Q9RC12 TYPE I S-SUBUNIT from Lactobacillus delbrueckii (subsp. lactis) (389 aa), FASTA scores: opt: 232, E(): 1.4e-07, (28.1% identity in 185 aa overlap); N-terminus of P72419|STY|SBLI from Salmonella typhimurium (434 aa), FASTA scores: opt: 221, E(): 8e-07, (28.45% identity in 130 aa overlap); C-terminus of P17222|PRRB_ECOLI from Escherichia coli strain CTR5X (401 aa), FASTA scores: opt: 197, E(): 2.8e-05, (27.05% identity in 148 aa overlap); etc. SEEMS TO BELONG TO TYPE-I RESTRICTION SYSTEM S METHYLASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30281203029214-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2782c|hsdS
MSRVEKVEKVRLGDHLDFSNGHTSGHTSPASEPGGRYPVYGANGVIGYSAQHNARGPLIVVGRVGSYCGSLRYCDSDVWVTDNALACRAKKPEETRYWYYALLGFGLNRYRAGSGQPLLSQGVLRNVSVSAVAAPDRPRIGEILGAFDDKIAANDRVIEAAEALMLAIVGRLSAYVPLSSLASRSTACLDAQHFDSTVAHYSFAAFDGGAQPSRVGGRTIRSAKLVVSQPCVLFPKLNPRIPRIWNITSLPSEMALASTEFVVLRPVGVDTSALWAALRQPDVLAELRQLVGGMTGSRQRIQPTQLLRVWVRDVRRLTPGHAAAIANLGALCNERRIESARLASCRDALLPLLMSGIDGLPAGR
      
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