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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
CommentsMb2788c, -, len: 260 aa. Equivalent to Rv2766c,len: 260 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 260 aa overlap). Probable short-chain dehydrogenase/reductase (EC 1.-.-.-), similar to others (from bacteria and eukaryota) e.g. Q9K3Y8|2SCG61.27c PUTATIVE SHORT CHAIN OXIDOREDUCTASE from Streptomyces coelicolor (253 aa), FASTA scores: opt: 722, E(): 7.4e-39,(44.75% identity in 248 aa overlap); Q93790|F54F3.4 HYPOTHETICAL SDR PROTEIN from Caenorhabditis elegans (260 aa), FASTA scores: opt: 613, E(): 6.9e-32, (41.7% identity in 247 aa overlap); O95162|O95162|SCAD-SRL PEROXISOMAL SHORT-CHAIN ALCOHOL DEHYDROGENASE from Homo sapiens (Human) (260 aa), FASTA scores: opt: 594, E(): 1.1e-30,(39.6% identity in 250 aa overlap); P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN] from Bacillus subtilis (246 aa), FASTA scores: opt: 504, E(): 4e-28, (37.2% identity in 247 aa overlap); etc. Also similar to many other Mycobacterium tuberculosis acyl-carrier proteins e.g. MTCY03C7.07 (38.5% identity in 244 aa overlap). Contains PS00061 Short-chain alcohol dehydrogenase family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY. Note that previously known as fabG5, a 3-oxoacyl-[acyl-carrier-protein].
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30321623032944-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2788c|Mb2788c
MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVLTARRQEAADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGSVDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPRIRVNAICPGVVRTRLAEALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
      
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