Gene Mb2790c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePPE43
Gene length1185 bp
IdentifierMb2790c
Location 3033468 bp
Protein summary information
Molecular mass38686.1 Da
Isoelectric point4.3334
Protein length394 amino acids
Orthologs
M. tuberculosis H37RvRv2768c
M. tuberculosis MTBC0mtbc0_002947
Cross-references
InterProIPR000030, IPR022171
UniProtKB/TrEMBLQ7TXX5
SWISS-MODELA0A1R3Y2K0
General annotation
TypeCDS
FunctionUnknown
Productppe family protein ppe43
CommentsMb2790c, PPE43, len: 394 aa. Equivalent to Rv2768c,len: 394 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 394 aa overlap). Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa),FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721, E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30334683034652-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2790c|PPE43
MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTTAWFVMATIRNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
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