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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE Sn-GLYCEROL-3-PHOSPHATE-BINDING LIPOPROTEIN UGPB
CommentsMb2857c, ugpB, len: 436 aa. Equivalent to Rv2833c,len: 436 aa, from Mycobacterium tuberculosis strain H37Rv,(99.3% identity in 436 aa overlap). Probable ugpB,Sn-glycerol-3-phosphate binding lipoprotein component of Sn-glycerol-3-phosphate transport system (see citation below), similar to various transporters substrate-binding periplasmic proteins e.g. Q9KDY2|BH1079 GLYCEROL-3-PHOSPHATE ABC TRANSPORTER (GLYCEROL-3-PHOSPHATE BINDING PROTEIN) from Bacillus halodurans (459 aa), FASTA scores: opt: 357, E(): 3.1e-14, (23.4% identity in 406 aa overlap); P72397|MALE PUTATIVE MALTOSE-BINDING PROTEIN from Streptomyces coelicolor (423 aa), FASTA scores: opt: 318, E(): 7e-12, (23.7% identity in 430 aa overlap); AAK78409|CAC0429 GLYCEROL-3-PHOSPHATE ABC-TRANSPORTER PERIPLASMIC COMPONENT from Clostridium acetobutylicum (447 aa), FASTA scores: opt: 305, E(): 4.5e-11, (27.15% identity in 438 aa overlap); P10904|UGPB_ECOLI|B3453 GLYCEROL-3-PHOSPHATE-BINDING PERIPLASMIC PROTEIN PRECURSOR from Escherichia coli strain K12 (438 aa); etc. Contains signal sequence and appropriately positioned prokaryotic lipoprotein attachment site (PS00013).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30957453097055-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2857c|ugpB
MDPLNRRQFLALAAAAAGVTAGCAGMGGGGSVKSGSGPIDFWSSHPGQSSAAERELIGRFQDRFPTLSVKLIDAGKDYDEVAQKFNAALIGTDVPDVVLLDDRWWFHFALIGVLTALDDLFGQVGVDTTDYVDSLLADYEFNGRHYAVPYARSTPLFYYNKAAWQQAGLPDRGLQSWSEFDEWGPELQRVVGAGRSAHGWANADLISWTFQGPNWAFGGAYSDKWTLTLTEPATIAAGNFYRNSIHGKGYAAVANDIANEFATGILASAVASTGSLPGITASARFDFGAAPLPTGPDAAPACPTGGAGLAIPAKLSEERKVNALKFIAFVTNPTNTAYFSQQTGYLPVRKSAVDDASERHYLADNPRARVALDQLPHTRTQDYARVFLPGGDRIISAGLESIGLRGADVTKTFTNIQKRLQVILDRQIMRKLAGHG
      
Bibliography
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