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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE MAGNESIUM CHELATASE
CommentsMb2875c, -, len: 629 aa. Equivalent to Rv2850c,len: 629 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 629 aa overlap). Possible magnesium-chelatase (EC 4.99.1.-), highly similar (but with gaps) to magnesium-chelatases from notably photosynthetic organisms involved in chlorophyll biosynthesis e.g. Q9RJ18|SCI8.35c PUTATIVE CHELATASE from Streptomyces coelicolor (672 aa), FASTA scores: opt: 1941,E(): 2.1e-85, (54.65% identity in 675 aa overlap); Q9HZQ5|PA2942 PROBABLE MAGNESIUM CHELATASE from Pseudomonas aeruginosa (338 aa), FASTA scores: opt: 991,E(): 2.7e-40, (49.45% identity in 368 aa overlap); O33549|BCHI MG PROTOPORPHYRIN IX CHELATASE SUBUNIT from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (334 aa), FASTA scores: opt: 833, E(): 9.4e-33, (50.65% identity in 318 aa overlap); O30819|BCHI_RHOSH MAGNESIUM-CHELATASE 38 KDA SUBUNIT from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (334 aa), FASTA scores: opt: 828, E(): 1.6e-32, (50.3% identity in 318 aa overlap); etc. Equivalent to AAK47242 from Mycobacterium tuberculosis strain CDC1551 (610 aa) but longer 19 aa. COULB BELONG TO THE MG-CHELATASE SUBUNITS D/I FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31146813116570-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2875c|Mb2875c
MKPYPFSAIVGHDRLRLALLLCAVRPEIGGALIRGEKGTAKSTAVRGLAALLSVATGSTETGLVELPLGATEDRVVGSLDLQRVMRDGEHAFSPGLLARAHGGVLYVDEVNLLHDHLVDILLDAAAMGRVHVERDGISHSHEARFVLIGTMNPEEGELRPQLLDRFGLTVDVQASRDIDVRVQVIRRRMAYEADPDAFVARYADADAELAHRIAAARATVDDVVLGDNELRRIAALCAAFDVDGMRADLVVARTAAAHAAWRGVRTVEEQDIQAAAELALPHRRRRDPFDDHGIDRDQLDEALALASVDPEPEPDPPGGGQSANEPASQPNSRSKSTEPGAPSSMGDDPPRPASPRLRSSPRPSAPPSKIFRTRALRVPGVGTGAPGRRSRARNASGSVVAAAEVSDPDAHGLHLFATLLAAGERAFGAGPLRPWPDDVRRAIRESREGNLVIFVVDASGSMAARDRMAAVSGATLSLLRDAYQRRDKVAVITFRQHEATLLLSPTSSAHIAGRRLARFSTGGKTPLAEGLLAARALIIREKVRDRARRPLVVVLTDGRATAGPDPLGRSRTAAAGLVAEGAAAVVVDCETSYVRLGLAAQLARQLGAPVVRLEQLHADYLVHAVRGVA
      
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