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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
CommentsMb2882c, -, len: 258 aa. Equivalent to Rv2857c,len: 258 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 258 aa overlap). Probable short-chain dehydrogenase/reductase (EC 1.-.-.-), highly similar to various dehydrogenases e.g. O88068|SCI35.33c PROBABLE DEHYDROGENASE (SDR FAMILY) from Streptomyces coelicolor (260 aa), FASTA scores: opt: 1208, E(): 2e-68, (72.35% identity in 253 aa overlap); Q9I376|PA1649 from Pseudomonas aeruginosa PROBABLE SHORT-CHAIN DEHYDROGENASE (253 aa), FASTA scores: opt: 569, E(): 2.1e-28, (39.2% identity in 255 aa overlap); Q9EX74|MLHA SDR-LIKE ENZYME from Rhodococcus erythropolis (246 aa), FASTA scores: opt: 567, E(): 2.8e-28, (41.15% identity in 248 aa overlap); etc. Also similar to many Mycobacterium tuberculosis dehydrogenases e.g. FABG3|Rv2002|MT2058|MTCY39.16c PUTATIVE OXIDOREDUCTASE (260 aa), FASTA score: (38.3% identity in 248 aa overlap). BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31250993125875-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2882c|Mb2882c
MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADELSGLFVPTDVCDEDAVNGLFDGAAETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASDDASFITASTFLVDGGISSAYVTPL
      
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