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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE AMIDASE AMIC (AMINOHYDROLASE)
CommentsMb2912c, amiC, len: 473 aa. Equivalent to Rv2888c,len: 473 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 473 aa overlap). Probable amiC,amidase (EC 3.5.1.4), equivalent to O33040|AMI3_MYCLE|AMIC|ML1596|MLCB250.65 PUTATIVE AMIDASE AMIC from Mycobacterium leprae (468 aa), FASTA scores: opt: 2361, E(): 4.2e-139, (76.7% identity in 468 aa overlap). Also similar to others e.g. Q9A8N0|CC1323 PUTATIVE 6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE from Caulobacter crescentus (521 aa), FASTA scores: opt: 925,E(): 7.4e-50, (36.55% identity in 465 aa overlap); O28325|YJ54_ARCFU|AF1954 PUTATIVE AMIDASE (EC 3.5.1.4) from Archaeoglobus fulgidus (453 aa), FASTA scores: opt: 659, E(): 2.2e-33, (31.1% identity in 460 aa overlap); Q55424|AMID_SYNY3|SLL0828 PUTATIVE AMIDASE from Synechocystis sp. strain PCC 6803 (506 aa), FASTA scores: opt: 643, E(): 2.4e-32, (30.7% identity in 466 aa overlap); etc. Also similar to O05835|AMI1_MYCTU|AMIA2|Rv2363|MT2432|MTCY27.17c PUTATIVE AMIDASE AMIA2 (484 aa), FASTA scores: opt: 656, E(): 3.6e-33, (35.9% identity in 465 aa overlap); and Q11056|AMI2_MYCTU|AMIB2|Rv1263|MT1301|MTCY50.19c PUTATIVE AMIDASE from Mycobacterium tuberculosis (462 aa), FASTA scores: opt: 650, E(): 8.2e-33, (33.45% identity in 472 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-poop). BELONGS TO THE AMIDASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31533803154801-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2912c|amiC
MSRVHAFVDDALGDLDAVALADAIRSGRVGRADVVEAAIARAEAVNPALNALAYAAFDVARDAAAMGTGQEAFFSGVPTFIKDNVDVAGQPSMHGTDAWEPYAAVADSEITRVVLGTGLVSLGKTQLSEFGFSAVAEHPRLGPVRNPWNTDYTAGASSSGSGALVAAGVVPIAHANDGGGSIRIPAACNGLVGLKPSRGRLPLEPEYRRLPVGIVANGVLTRTVRDTAAFYREAERLWRNHQLPPVGDVTSPVKQRLRIAVVTRSVLREASPEVRQLTLKLAGLLEELGHRVEHVDHPPAPASFVDDFVLYWGFLALAQVRSGRRTFGRTFDPTRLDELTLGLARHTGRNLHRLPLAIMRLRMLRRRSVRFFGTYDVLLTPTVAEATPQVGYLAPTDYQTVLDRLSSWVVFTPVQNVTGVPAISLPLAQSADGMPVGMMLSADTGREALLLELAYELEEARPWARIHAPNIAE
      
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