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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE RIBONUCLEASE III RNC (RNASE III)
CommentsMb2950c, rnc, len: 240 aa. Equivalent to Rv2925c,len: 240 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 240 aa overlap). Probable rnc,ribonuclease III (RNase III) (EC 3.1.26.3), equivalent to O69469|RNC_MYCLE RIBONUCLEASE III from Mycobacterium leprae (238 aa). Also highly similar to other ribonucleases III e.g. Q9ZBQ7|RNC_STRCO from Streptomyces coelicolor (272 aa), FASTA scores: opt: 889, E(): 5.4e-51,(62.2% identity in 225 aa overlap) (N-terminus longer 21 aa); P51833|RNC_BACSU from Bacillus subtilis (249 aa),FASTA scores: opt: 493, E(): 5e-25, (43.25% identity in 215 aa overlap); P05797|RNC_ECOLI|RNC|B2567|Z3848|ECS3433 from Escherichia coli strain O157:H7 and K12 (226 aa),FASTA scores: opt: 459, E(): 7.9e-23, (41.8% identity in 213 aa overlap); etc. Contains PS00517 Ribonuclease III family signature.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31964023197124-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2950c|rnc
MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA
      
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