Gene Mb2955
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | fatty-acid-amp ligase fadd26 (fatty-acid-amp synthetase) (fatty-acid-amp synthase) |
| Comments | Mb2955, fadD26, len: 583 aa. Equivalent to Rv2930,len: 583 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 583 aa overlap). fadD26, fatty-acid-CoA synthetase (EC 6.2.1.-) (see first and third citations below), equivalent to Q9Z5K5|FADD26|ML2358|MLCB12.03c PROBABLE ACYL-CoA SYNTHASE from Mycobacterium leprae (583 aa), FASTA scores: opt: 3026, E(): 9.2e-180, (76.85% identity in 583 aa overlap). Also highly similar to many e.g. Q9CD84|ML0132 PUTATIVE ACYL-CoA SYNTHETASE from Mycobacterium leprae (680 aa), FASTA scores: opt: 2324,E(): 3.2e-136, (61.35% identity in 572 aa overlap); P71495 ACYL-CoA SYNTHASE from Mycobacterium bovis (582 aa), FASTA scores: opt: 2304, E(): 5e-135, (59.85% identity in 583 aa overlap); etc. Also highly similar to others from Mycobacterium tuberculosis e.g. Q50586|FD25_MYCTU|RV1521|MTCY19G5.07 PUTATIVE FATTY-ACID--CoA LIGASE (583 aa), FASTA scores: opt: 2188,E(): 7.6e-128, (57.55% identity in 584 aa overlap); etc. BELONGS TO THE ATP-DEPENDENT AMP-BINDING ENZYME FAMILY. N-terminus shortened since first submission. Note that Rv2930|fadD26 belongs to the transcriptional unit Rv2930|fadD26-Rv2939|papA5 (proven experimentaly). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3200270 | 3202021 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2955|fadD26
MPVTDRSVPSLLQERADQQPDSTAYTYIDYGSDPKGFADSLTWSQVYSRACIIAEELKLCGLPGDRVAVLAPQGLEYVLAFLGALQAGFIAVPLSTPQYGIHDDRVSAVLQDSKPVAILTTSSVVGDVTKYAASHDGQPAPVVVEVDLLDLDSPRQMPAFSRQHTGAAYLQYTSGSTRTPAGVIVSHTNVIANVTQSMYGYFGDPAKIPTGTVVSWLPLYHDMGLILGICAPLVARRRAVLMSPMSFLRRPARWMQLLATSGRCFSAAPNFAFELAVRRTSDQDMAGLDLRDVVGIVSGSERIHVATVRRFIERFAPYNLSPTAIRPSYGLAEATLYVAAPEAGAAPKTVRFDYEQLTAGQARPCGTDGSVGTELISYGSPDPSSVRIVNPETMVENPPGVVGEIWVHGDHVTMGYWQKPKQTAQVFDAKLVDPAPAAPEGPWLRTGDLGVISDGELFIMGRIKDLLIVDGRNHYPDDIEATIQEITGGRAAAIAVPDDITEQLVAIIEFKRRGSTAEEVMLKLRSVKREVTSAISKSHSLRVADLVLVSPGSIPITTSGKIRRSACVERYRSDGFKRLDVAV
Bibliography
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