Gene Mb2975c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2975c
Gene length1146 bp
IdentifierMb2975c
Location 3259791 bp
Protein summary information
Molecular mass41347.6 Da
Isoelectric point9.4232
Protein length381 amino acids
Orthologs
M. tuberculosis H37RvRv2951c
M. tuberculosis MTBC0mtbc0_003133
Cross-references
UniProtKB/TrEMBLX2BM02, Q7TXK4
SWISS-MODELQ7TXK4
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE OXIDOREDUCTASE
CommentsMb2975c, -, len: 381 aa. Equivalent to Rv2951c,len: 381 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 381 aa overlap). Possible oxidoreductase (EC 1.-.-.-), equivalent to Q9CD85 PUTATIVE OXIDOREDUCTASE from Mycobacterium leprae (382 aa), FASTA scores: opt: 2225, E(): 7.6e-134, (84.8% identity in 382 aa overlap); and similar to O30260 CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium leprae (363 aa), FASTA scores: opt: 652, E(): 6.1e-34, (32.55% identity in 344 aa overlap). Also similar to various oxidoreductases e.g. O29071|AF1196 N5,N10-METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE from Archaeoglobus fulgidus (348 aa), FASTA scores: opt: 381, E(): 9.7e-17, (27.7% identity in 354 aa overlap); Q58929|MER|MJ1534 F420-DEPENDENT METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE (EC 1.5.99.-) from Methanococcus jannaschii (331 aa), FASTA scores: opt: 372, E(): 3.5e-16, (30.85% identity in 295 aa overlap); Q9UXP0 PUTATIVE F420-DEPENDENT N5,N10-METHYLENE-TETRAHYDROMETHANOPTERIN REDUCTASE from Methanolobus tindarius (326 aa), FASTA scores: opt: 343,E(): 2.4e-14, (27.4% identity in 314 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32597913260936-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2975c|Mb2975c
MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL
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