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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE OXIDOREDUCTASE
CommentsMb2975c, -, len: 381 aa. Equivalent to Rv2951c,len: 381 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 381 aa overlap). Possible oxidoreductase (EC 1.-.-.-), equivalent to Q9CD85 PUTATIVE OXIDOREDUCTASE from Mycobacterium leprae (382 aa), FASTA scores: opt: 2225, E(): 7.6e-134, (84.8% identity in 382 aa overlap); and similar to O30260 CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium leprae (363 aa), FASTA scores: opt: 652, E(): 6.1e-34, (32.55% identity in 344 aa overlap). Also similar to various oxidoreductases e.g. O29071|AF1196 N5,N10-METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE from Archaeoglobus fulgidus (348 aa), FASTA scores: opt: 381, E(): 9.7e-17, (27.7% identity in 354 aa overlap); Q58929|MER|MJ1534 F420-DEPENDENT METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE (EC 1.5.99.-) from Methanococcus jannaschii (331 aa), FASTA scores: opt: 372, E(): 3.5e-16, (30.85% identity in 295 aa overlap); Q9UXP0 PUTATIVE F420-DEPENDENT N5,N10-METHYLENE-TETRAHYDROMETHANOPTERIN REDUCTASE from Methanolobus tindarius (326 aa), FASTA scores: opt: 343,E(): 2.4e-14, (27.4% identity in 314 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32597913260936-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2975c|Mb2975c
MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL
      
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