Gene Mb2977 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2977
Gene length1257 bp
IdentifierMb2977
Location 3261967 bp
Protein summary information
Molecular mass45104.2 Da
Isoelectric point9.3402
Protein length418 amino acids
Orthologues
M. tuberculosisRv2953
Cross-references
UniProtKB/TrEMBLX2BM75, Q7TXK2
SWISS-MODELQ7TXK2
General annotation
TypeCDS
FunctionUnknown
Productenoyl reductase
CommentsMb2977, -, len: 418 aa. Equivalent to Rv2953, len: 418 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 418 aa overlap). Conserved hypothetical protein, equivalent to Q9CD87|ML0129 HYPOTHETICAL PROTEIN from Mycobacterium leprae (418 aa),FASTA scores: opt: 2357, E(): 2.7e-143, (86.6% identity in 418 aa overlap). Also highly similar to Q9X7N5|SC5F2A.12c CONSERVED HYPOTHETICAL PROTEIN from Streptomyces coelicolor (396 aa), FASTA scores: opt: 491, E(): 7e-24,(38.35% identity in 417 aa overlap); and similar to other hypothetical proteins e.g. Q9VG81 CG5167 PROTEIN from Drosophila melanogaster (Fruit fly) (431 aa), FASTA scores: opt: 393, E(): 1.4e-17, (26.55% identity in 433 aa overlap); Q9GZE9|F22F7.1 HYPOTHETICAL PROTEIN from Caenorhabditis elegans (426 aa), FASTA scores: opt: 338,E(): 4.6e-14, (27.05% identity in 425 aa overlap); P73855|SLL1601 HYPOTHETICAL 44.8 KDA PROTEIN from Synechocystis sp. (strain PCC 6803) (414 aa), FASTA scores: opt: 565, E(): 1.3e-28, (35.7% identity in 409 aa overlap); etc. Also highly similar to other proteins from Mycobacterium tuberculosis e.g. RV2449C|O53176|MTV008.05C HYPOTHETICAL 44.4 KDA PROTEIN (419 aa), FASTA scores: opt: 1835, E(): 7e-110, (67.55% identity in 419 aa overlap); etc.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32619673263223+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2977|Mb2977
MSPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSERLRGVRMMLGPNAADWPLILADASQPLTLEAMAARAQVVLTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVEDGTGELCDTDLVLRSFSQRWVSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPELAGFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVTGTVAGTIGLGNKYFDRLPRRLVERVTPKPGTGPSRKTQERGHYTFETYTTTTTGARYRATFAHNVDAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGDALLARLPGAGVVMGTTRLS
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