Gene Mb2988
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE FORMYLTETRAHYDROFOLATE DEFORMYLASE PURU (FORMYL-FH(4) HYDROLASE) |
| Comments | Mb2988, purU, len: 310 aa. Equivalent to Rv2964,len: 310 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 310 aa overlap). Probable purU,formyltetrahydrofolate deformylase (EC 3.5.1.10), highly similar to others e.g. Q9RWT1|DR0584 FORMYLTETRAHYDROFOLATE DEFORMYLASE from Deinococcus radiodurans (298 aa), FASTA scores: opt: 1005, E(): 4.9e-52, (52.25% identity in 297 aa overlap); Q9K7U4 FORMYLTETRAHYDROFOLATE DEFORMYLASE from Bacillus halodurans (289 aa), FASTA scores: opt: 982, E(): 1.1e-50,(51.8% identity in 280 aa overlap); Q55135|PURU_SYNY3|SLL0070 FORMYLTETRAHYDROFOLATE DEFORMYLASE from Synechocystis sp. strain PCC 6803 (284 aa), FASTA scores: opt: 839, E(): 2.9e-42, (48.2% identity in 280 aa overlap); etc. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3273218 | 3274150 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2988|purU
MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIAAVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVADKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANHPDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGNVDLVVLARYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRAVLWHCQDRVIVHHNQTIVF
Bibliography
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