Gene Mb2993c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2993c
Gene length768 bp
IdentifierMb2993c
Location 3280398 bp
Protein summary information
Molecular mass26861.5 Da
Isoelectric point5.7746
Protein length255 amino acids
Orthologs
M. tuberculosis H37RvRv2969c
M. tuberculosis MTBC0mtbc0_003153
Cross-references
InterProIPR012336
UniProtKB/TrEMBLQ7TXI9
SWISS-MODELA0A1R3Y3I9
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CONSERVED MEMBRANE OR SECRETED PROTEIN
CommentsMb2993c, -, len: 255 aa. Equivalent to Rv2969c,len: 255 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 255 aa overlap). Possible conserved membrane or exported protein, equivalent to Q9CBS4|ML1667 POSSIBLE CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (264 aa), FASTA scores: opt: 1101, E(): 9.9e-68,(65.9% identity in 258 aa overlap); and highly similar to O69463 PUTATIVE TRANSMEMBRANE PROTEIN from Mycobacterium leprae (258 aa), FASTA scores: opt: 1097, E(): 1.8e-67,(65.5% identity in 258 aa overlap). C-terminus also highly similar to Q9KK65|996A160 EXPORTED PROTEIN (FRAGMENT) from Mycobacterium avium (85 aa), FASTA scores: opt: 418, E(): 2e-21, (72.95% identity in 85 aa overlap). Also weakly similar to membrane or exported proteins e.g. Q9S2U7|SC4G6.04c PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (275 aa), FASTA scores: opt: 312,E(): 7.6e-14, (28.25% identity in 230 aa overlap); Q9XAB6|SCC22.22C PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (255 aa), FASTA scores: opt: 181,E(): 6.4e-05, (27.0% identity in 226 aa overlap); etc. Also some similarity with P72001|PKNE_MYCTU from Mycobacterium tuberculosis (566 aa), FASTA scores: opt: 264, E(): 2.3e-10, (30.5% identity in 177 aa overlap).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32803983281165-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2993c|Mb2993c
MADKSKRPPRFDLKSADGSFGRLVQIGGTTIVVVFAVVLVFYIVTSRDDKKDGVAGPGDAVRVTSSKLVTQPGTSNPKAVVSFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKDIQPAELGKDFPDNARLIELAREAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIVGDVPGIDSAAATATS
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