Gene Mb3006c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(P)+] GPDA2 (NAD(P)H-DEPENDENT GLYCEROL-3-PHOSPHATE DEHYDROGENASE) |
| Comments | Mb3006c, gpdA2, len: 334 aa. Equivalent to Rv2982c,len: 334 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 334 aa overlap). Probable gpdA2 (alternate gene name: gpsA), glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94), equivalent to Q9CBR9|GPDA_MYCLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(P)+] from Mycobacterium leprae (349 aa), FASTA scores: opt: 1686, E(): 1.7e-95, (77.95% identity in 349 aa overlap). Also highly similar to others e.g. Q9ZBS0|GPDA_STRCO from Streptomyces coelicolor (336 aa),FASTA scores: opt: 1165, E(): 9.8e-64, (56.25% identity in 327 aa overlap); P46919|GPDA_BACSU from Bacillus subtilis (345 aa), FASTA scores: opt: 872, E(): 7.5e-46, (44.9% identity in 325 aa overlap); P37606|GPDA_ECOLI|GPSA|B3608|Z5035|ECS4486. from Escherichia coli strain O157:H7 and K12 (339 aa), FASTA scores: opt: 799, E(): 2.1e-41, (42.9% identity in 331 aa overlap); etc. Also highly similar to O53761|GPD2_MYCTU PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE from Mycobacterium tuberculosis (341 aa), FASTA scores: opt: 740, E(): 8.4e-38, (40.35% identity in 322 aa overlap). BELONGS TO THE NAD-DEPENDENT GLYCEROL-3-PHOSPHATE DEHYDROGENASE FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3294555 | 3295559 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3006c|gpdA2
MAGIASTVAVMGAGAWGTALAKVLADAGGEVTLWARRAEVADQINTTRYNPDYLPGALLPPSIHATADAEEALGGASTVLLGVPAQTMRANLERWAPLLPEGATLVSLAKGIELGTLMRMSQVIISVTGAEPAQVAVISGPNLASEIAECQPAATVVACSDSGRAVALQRALNSGYFRPYTNADVVGTEIGGACKNIIALACGMAVGIGLGENTAAAIITRGLAEIIRLGTALGANGATLAGLAGVGDLVATCTSPRSRNRSFGERLGRGETLQSAGKACHVVEGVTSCESVLALASSYDVEMPLTDAVHRVCHKGLSVDEAITLLLGRRTKPE
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