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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productglutamyl-trna synthetase glts (glutamate--trna ligase) (glutamyl-trna synthase) (glurs)
CommentsMb3016c, gltS, len: 490 aa. Equivalent to Rv2992c,len: 490 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 490 aa overlap). Probable gltS (alternate gene name: gltX), glutamyl-tRNA synthase (EC 6.1.1.17), equivalent to O33120|SYE_MYCLE GLUTAMYL-TRNA SYNTHETASE from Mycobacterium leprae (502 aa), FASTA scores: opt: 2660, E(): 2.3e-163, (81.35% identity in 488 aa overlap). Also highly similar to others e.g. O86528|SYE_STRCO from Streptomyces coelicolor (494 aa),FASTA scores: opt: 1777, E(): 1.4e-106, (57.45% identity in 484 aa overlap); P22250|SYE_BACSU from Bacillus subtilis (483 aa), FASTA scores: opt: 1099, E(): 5.4e-63,(38.45% identity in 489 aa overlap); O51345|SYE_BORBU|GLTX|BB0372 from Borrelia burgdorferi (Lyme disease spirochete) (490 aa), FASTA scores: opt: 1009, E(): 3.3e-57, (34.85% identity in 491 aa overlap); etc. BELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY. TBparse score is 0.891.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS33053653306837-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3016c|gltS
MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDAQRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTVRLRDHLDTHGHHIALDEAAFAAAAELVQTRIVVLGDAWELLKFFNDDQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVGHA
      
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