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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE)
CommentsMb3017c, -, len: 239 aa. Equivalent to Rv2993c,len: 239 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 239 aa overlap). Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-), equivalent to O33119|ML1689|MLCB637.28 POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE- 1,7-DIOATE ISOMERASE from Mycobacterium leprae (242 aa), FASTA scores: opt: 1427,E(): 4.4e-86, (85.9% identity in 241 aa overlap). Also similar to others e.g. Q9LBE3|DR1609 from Deinococcus radiodurans (250 aa), FASTA scores: opt: 723, E(): 5.5e-40, (49.05% identity in 216 aa overlap); O27551|MTH1507 from Methanothermobacter thermautotrophicus (260 aa), FASTA scores: opt: 708, E(): 5.4e-39, (52.1% identity in 213 aa overlap); Q9HQR6|VNG1037G|HPCE from Halobacterium sp. (strain NRC-1) (244 aa), FASTA scores: opt: 590, E(): 2.7e-31, (43.65% identity in 220 aa overlap); etc. Start chosen by homology, but ORF could continue upstream. TBparse score is 0.896.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS33068343307553-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3017c|Mb3017c
MTAREIAEHPFGTPTFTGRSWPLADVRLLAPILASKVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPANASPVHFEGELAIVIGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSDGQWTRAKGHDTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGVGPIEDGDTVSITIEGIGTLTNPVVRKGKP
      
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