Gene Mb3074c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF2 (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN) |
| Comments | Mb3074c, nrdF2, len: 324 aa. Equivalent to Rv3048c,len: 324 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 324 aa overlap). nrdF2,ribonucleoside-diphosphate reductase, beta chain (EC 1.17.4.1) (see citation below), equivalent to Q9CBQ2|RIR2_MYCL|NRDF|ML1731 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN from Mycobacterium leprae (325 aa),FASTA scores: opt: 2009, E(): 1.3e-123, (93.5% identity in 324 aa overlap). Also similar to other ribonucleoside-diphosphate reductases e.g. Q9XD62|NRDF from Corynebacterium glutamicum (Brevibacterium flavum) (334 aa), FASTA scores: opt: 1648, E(): 4.2e-100, (78.35% identity in 314 aa overlap); O69274|NRDF from Corynebacterium ammoniagenes (Brevibacterium ammoniagenes) (329 aa), FASTA scores: opt: 1626, E(): 1.1e-98, (75.3% identity in 320 aa overlap); P37146|NRDF|B2676 from Escherichia coli (319 aa), FASTA scores: opt: 1569, E(): 5.7e-95, (71.3% identity in 317 aa overlap). Contains PS00368 Ribonucleotide reductase small subunit signature. BELONGS TO THE RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE SMALL CHAIN FAMILY. COFACTOR: BINDS 2 IRON IONS (BY SIMILARITY). Note that previously known as nrdG. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3364964 | 3365938 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3074c|nrdF2
MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENRNLQRKAEIVLQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDDDWDF
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