Gene Mb3077c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | ribonucleoside-diphosphate reductase (alpha chain) nrde (ribonucleotide reductase small subunit) (r1f protein) |
| Comments | Mb3077c, nrdE, len: 693 aa. Equivalent to Rv3051c,len: 693 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 693 aa overlap). nrdE,ribonucleotide-diphosphate reductase, alpha chain (EC 1.17.4.1) (see citations below), equivalent to Q9CBQ0|NRDE|ML1734 from Mycobacterium leprae (693 aa),FASTA scores: opt: 4259,E(): 0, (93.2% identity in 693 aa overlap). Similar to other Ribonucleoside-diphosphate reductases e.g. Q9XD63|NRDE from Corynebacterium glutamicum (Brevibacterium flavum) (707 aa), FASTA scores: opt: 3683,E(): 0, (79.35% identity in 693 aa overlap); O69273|NRDE from Corynebacterium ammoniagenes (Brevibacterium ammoniagenes) (720 aa), FASTA scores: opt: 3555, E(): 1.7e-214, (76.1% identity in 694 aa overlap); P39452|NRDE|B2675 from Escherichia coli (713 aa), FASTA scores: opt: 3430, E(): 1.1e-206, (73.6% identity in 693 aa overlap); etc. Equivalent to AAK47468|MT3137 from Mycobacterium tuberculosis strain CDC1551 (725 aa) but shorter in N-terminus. Contains PS00089 Ribonucleotide reductase large subunit signature. BELONGS TO THE RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE LARGE CHAIN FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3368645 | 3370726 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3077c|nrdE
MLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTALAELLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGKITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTVLYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIPTQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML
Bibliography
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