Gene Mb3112 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3112
Gene length831 bp
IdentifierMb3112
Location 3407467 bp
Protein summary information
Molecular mass29217.5 Da
Isoelectric point9.656
Protein length276 amino acids
Orthologs
M. tuberculosis H37RvRv3085
M. tuberculosis MTBC0mtbc0_003279
Cross-references
InterProIPR002198, IPR002347, IPR016040, IPR020904
UniProtKB/TrEMBLQ7TXA4
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
CommentsMb3112, -, len: 276 aa. Equivalent to Rv3085, len: 276 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 276 aa overlap). Probable short-chain dehydrogenase/reductase (EC 1.-.-.-), similar to various oxidoreductases in the short chain dehydrogenases/reductases family e.g. Q9CC98|ML1094 SHORT CHAIN ALCOHOL DEHYDROGENASE from Mycobacterium leprae (277 aa), FASTA scores: opt: 1059, E(): 4.8e-56, (61.65% identity in 266 aa overlap); Q9I3H6|PA1537 PROBABLE SHORT-CHAIN DEHYDROGENASE from Pseudomonas aeruginos (295 aa), FASTA scores: opt: 858, E(): 4.7e-44, (48.4% identity in 285 aa overlap); Q9CBP7|ML1740 POSSIBLE SHORT CHAIN REDUCTASE from Mycobacterium leprae (312 aa), FASTA scores: opt: 500, E(): 1e-22, (36.6% identity in 257 aa overlap); etc. Also similar to mycobacterium proteins O50460|Rv1245c|MTV006.17c DEHYDROGENASE SIMILAR TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY (276 aa),FASTA scores: opt: 1200, E(): 1.9e-64, (65.2% identity in 273 aa overlap); and P95101|Rv3057c|MTCY22D7.24 HYPOTHETICAL DEHYDROGENASE (287 aa). Contains PS00061 Short-chain alcohol dehydrogenase family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS34074673408297+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3112|Mb3112
MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSDRLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVARNATVADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLEAKAVDVLARIMGSSYQRLVAAGVAKFFPWAK
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