Gene Mb3148c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePPE49
Gene length1176 bp
IdentifierMb3148c
Location 3444248 bp
Protein summary information
Molecular mass38613.6 Da
Isoelectric point6.5167
Protein length391 amino acids
Orthologs
M. tuberculosis H37RvRv3125c
M. tuberculosis MTBC0mtbc0_003322
Cross-references
InterProIPR000030, IPR022171
UniProtKB/TrEMBLQ7TX76
SWISS-MODELA0A1R3Y376
General annotation
TypeCDS
FunctionUnknown
Productppe family protein ppe49
CommentsMb3148c, PPE49, len: 391 aa. Equivalent to Rv3125c,len: 391 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 391 aa overlap). Member of the M. tuberculosis PPE family, similar to other e.g. P95247|Rv2352c|MTCY98.21c (391 aa), FASTA scores: opt: 1576, E(): 3.8e-72, (62.55% identity in 398 aa overlap),MTCY98.0029c, MTCY03A2.22c, MTCY10G2.10, MTCY02B10.25c,MTCI364.08, M TCY21C12.09c, MTCY48.17.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS34442483445423-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3148c|PPE49
MVLGFSWLPPEINSARMFAGAGSGPLFAAASAWEGLAVDLWASASSFESVLAALTTGPWTGPASMSMAAAASPYVGWLSTVASQAQLAAIQARAAATAFEAALAATVHPTAVTANRVSLASLIAANVLGQNTPAIAATEFDYLEMWAQDVAAMVGYHAGAKSVAATLAPFSLPPVSLAGLAAQVGTQVAGMATTASAAVTPVVEGAMASVPTVMSGMQSLVSQLPLQHASMLFLPVRILTSPITTLASMARESATRLGPPAGGLAAANTPNPSGAAIPAFKPLGGRELGAGMSAGLGQAQLVGSMSVPPTWQGSIPISMASSAMSGLGVPPNPVALTQAAGAAGGGMPMMLMPMSISGAGAGMPGGLMDRDGAGWHVTQARLTVIPRTGVG
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