Gene Mb3156c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | TWO COMPONENT SENSOR HISTIDINE KINASE DEVS |
| Comments | Mb3156c, devS, len: 578 aa. Equivalent to Rv3132c,len: 578 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 578 aa overlap). devS, membrane-bound two component sensor histidine kinase (EC 2.7.3.-) (see citations below; dev for Differentially Expressed in Virulent strain), similar to others two component sensors e.g. Q9RI43|SCJ12.15c PUTATIVE TWO-COMPONENT SENSOR from Streptomyces coelicolor (585 aa), FASTA scores: opt: 1305,E(): 2.5e-69, (41.35% identity in 573 aa overlap); Q9ZBY4|SCD78.15 PUTATIVE TWO COMPONENT SENSOR from Streptomyces coelicolor (560 aa), FASTA scores: opt: 1194,E(): 8.1e-63, (41.05% identity in 558 aa overlap); O85371|CPRS TWO COMPONENT REGULATOR from Rhodococcus sp (563 aa), FASTA scores: opt: 803, E(): 8.3e-40, (38.4% identity in 552 aa overlap); Q9L094|SCC24.23 PUTATIVE TWO-COMPONENT SENSOR HISTIDINE KINASE from Streptomyces coelicolor (similarity only in C-terminus for this one); etc. Also highly similar to mycobacterium O53473|Rv2027c|MTV018.14c PUTATIVE MEMBRANE PROTEIN (573 aa), FASTA scores: opt: 2333, E(): 7.6e-130, (61.45% identity in 576 aa overlap). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3451301 | 3453037 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3156c|devS
MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASTVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ
Bibliography
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