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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productppe family protein ppe50
CommentsMb3159, PPE50, len: 381 aa. Similar to 5' end of Rv3135, len: 132 aa, from Mycobacterium tuberculosis strain H37Rv, (88.5% identity in 131 aa overlap). Member of the Mycobacterium tuberculosis Ala-, Gly-rich PPE family, similar to P95190|Rv3136|MTCY03A2.22c (380 aa),FASTA scores: opt: 494, E(): 6.7e-25, (57.25% identity in 131 aa overlap) (next ORF downstream), MTY21C12_9,MTCY3C7_24, MTCI125_27, MTV049_12, MTV049_9, MTV049_11 ,MTCY274_24 etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a large 1337 bp insertion leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (381 aa versus 132 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS34551063456251+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3159|PPE50
MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGPASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKALIASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLAAQNAAVTQAATNSAGNTPTALSQLSSFLSQAVEAPTGWPNILPDDFTILDGILAAYATVGVTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGIDAALSSAEKGAAASMHDAVLASAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG
      
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