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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE NADH DEHYDROGENASE I (CHAIN B) NUOB (NADH-UBIQUINONE OXIDOREDUCTASE CHAIN B)
CommentsMb3170, nuoB, len: 184 aa. Equivalent to Rv3146,len: 184 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 184 aa overlap). Probable nuoB, NADH dehydrogenase, chain B (EC 1.6.5.3), similar to others e.g. Q9XAQ5|NUOB from Streptomyces coelicolor (184 aa),FASTA scores: opt: 989, E(): 1.4e-56, (78.25% identity in 184 aa overlap); Q56218|NQO6_THETH|NQO6 from Thermus aquaticus (subsp. thermophilus) (181 aa), FASTA scores: opt: 720, E(): 2.6e-39, (64.45% identity in 152 aa overlap); Q9RU87|DR1505 from Deinococcus radiodurans (181 aa), FASTA scores: opt: 719, E(): 3e-39, (62.6% identity in 155 aa overlap); etc. BELONGS TO THE COMPLEX I 20 KDA SUBUNIT FAMILY. MAY CONTAIN AN IRON-SULFUR 4FE-4S CLUSTER. TBparse score is 0.912.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS34671863467740+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3170|nuoB
MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERFSATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLHAILKLHEKIQQMPLGINRERAIAEAEEAALLARPTIEMRGLLR
      
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