Gene Mb3179
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE NADH DEHYDROGENASE I (CHAIN K) NUOK (NADH-UBIQUINONE OXIDOREDUCTASE CHAIN K) |
| Comments | Mb3179, nuoK, len: 99 aa. Equivalent to Rv3155,len: 99 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 99 aa overlap). Probable nuoK,integral membrane NADH dehydrogenase I, chain K (EC 1.6.5.3), similar to others e.g. Q9XAR4|NUOK from Streptomyces coelicolor (99 aa), FASTA scores: opt: 509,E(): 2.7e-31, (78.55% identity in 98 aa overlap); Q56226|NQOB_THETH|NQO11 from Thermus aquaticus (subsp. thermophilus) (95 aa), BLAST scores: initn: 298, init1: 180, bits: 85.7, FASTA scores: opt: 313, E(): 9.4e-17,(53.7% identity in 95 aa overlap); Q9RU97|DR1495 from Deinococcus radiodurans (103 aa), FASTA scores: opt: 309,E(): 2e-16, (52.0% identity in 100 aa overlap); etc. But also similarity with NADH-PLASTOQUINONE OXIDOREDUCTASES CHAIN 4L e.g. Q9MUL4|NULC_MESVI|NDHE from Mesostigma viride (EC 1.6.5.3) (CATALYTIC ACTIVITY: NADH + PLASTOQUINONE = NAD(+) + PLASTOQUINOL) (101 aa), FASTA scores: opt: 280, E(): 2.8e-14, (40.6% identity in 101 aa overlap); and P06261|NULC_TOBAC|NDHE|NDH4L from Nicotiana tabacum (Common tobacco) (101 aa), FASTA scores: opt: 259,E(): 1e-12, (43.0% identity in 93 aa overlap). SIMILAR TO POLYPEPTIDE 4L OF THE NADH-UBIQUINOL OXIDOREDUCTASE OF CHLOROPLASTS OR MITOCHONDRIA. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3477033 | 3477332 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3179|nuoK
MNPANYLYLSVLLFTIGASGVLLRRNAIVMFMCVELMLNAVNLAFVTFARMHGHLDAQMIAFFTMVVAACEVVVGLAIIMTIFRTRKSASVDDANLLKG
Bibliography
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