Gene Mb3186c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3186c
Gene length1149 bp
IdentifierMb3186c
Location 3487242 bp
Protein summary information
Molecular mass42518.2 Da
Isoelectric point5.0079
Protein length382 amino acids
Orthologs
M. tuberculosis H37RvRv3161c
M. tuberculosis MTBC0mtbc0_003360
Cross-references
InterProIPR001663, IPR015879, IPR017941
UniProtKB/TrEMBLQ7TX50
SWISS-MODELA0A1R3Y3A6
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE DIOXYGENASE
CommentsMb3186c, -, len: 382 aa. Equivalent to Rv3161c,len: 382 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 382 aa overlap). Possible dioxygenase (EC 1.-.-.-), similar to subunit of several dioxygenases and related proteins e.g. BAB50510|MLR3662 DIOXYGENASE,ALPHA SUBUNIT from Rhizobium loti (Mesorhizobium loti) (400 aa), FASTA scores: opt: 413, E(): 6.2e-20, (28.4% identity in 331 aa overlap); Q9A3T0|CC3122 RIESKE 2FE-2S FAMILY PROTEIN from Caulobacter crescentus (404 aa), FASTA scores: opt: 405, E(): 2.1e-19, (27.95% identity in 372 aa overlap); Q9HTF4|PA5410 PROBABLE RING HYDROXYLATING DIOXYGENASE, ALPHA-SUBUNIT from Pseudomonas aeruginosa (429 aa), FASTA scores: opt: 392, E(): 1.6e-18, (25.8% identity in 399 aa overlap); Q9AGK6|PHTAA PHTHALATE DIOXYGENASE LARGE SUBUNIT from Arthrobacter keyseri (473 aa), FASTA scores: opt: 385, E(): 5.2e-18, (34.0% identity in 206 aa overlap); P76253|YEAW_ECOLI PUTATIVE DIOXYGENASE, ALPHA SUBUNIT from Escherichia coli (374 aa),FASTA scores: opt: 376, E(): 1.7e-17, (27.05% identity in 344 aa overlap); etc. TBparse score is 0.932.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS34872423488390-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3186c|Mb3186c
MLSTDNRAELGDILTDIGDYLDDNPPALSLPPAAYTSSELWQLERERIFNRSWMLVAHVDQLAKTGDYVTVSVAGEPVMVVRDVDGQLHALSPICRHRLMLMVEPGAGRIDTLTCQYHLWRYGLDGRLRGAPHMAANLDFNRRECRLPQFAVATWNGLVWINLDADAEPIAAHLDLTDDEFAGYRLGEMVQVESWSHEWRANWKVAAENGHENYHVLGLHRQTLEPFVPGGGDLDVRQYSRWALRLRVPFTVPVEAKSLQLNEVQKSNLVVLWTFPNSALAIAGERVVWFGFIPQSIDRVQVLGGVLTTPELAADAAATAQTSQFVMAMINDEDRLGLEAVQVGAGSRFAERGHLSSKEWPGMLAFYRNLAMALVGDHPGAS
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