Gene Mb3224c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE NADH PYROPHOSPHATASE NUDC (NAD+ DIPHOSPHATASE) (NAD+ PYROPHOSPHATASE) (NADP PYROPHOSPHATASE) |
| Comments | Mb3224c, nudC, len: 313 aa. Equivalent to Rv3199c,len: 313 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 313 aa overlap). Probable nudC, NADH pyrophosphatase (EC 3.6.1.22), similar in particular to Q9CXN4|4933433B15RIK from Mus musculus (Mouse) (356 aa),FASTA scores: opt: 493, E(): 7.4e-24, (39.65% identity in 232 aa overlap); Q9ABG1|CC0266 MUTT/NUDIX FAMILY PROTEIN from Caulobacter crescentus (313 aa), FASTA scores: opt: 479, E(): 5.1e-23, (38.3% identity in 222 aa overlap); O86062|NUDC_PSEAE|NUDC|PA1823 NADH PYROPHOSPHATASE from Pseudomonas aeruginosa (278 aa), FASTA scores: opt: 371,2 E(): 3e-16, (43.15% identity in 153 aa overlap); Q9RV62|NUDC_DEIRA|NUDC|DR1168 NADH PYROPHOSPHATASE from Deinococcus radiodurans (280 aa), FASTA scores: opt: 363,E(): 9.6e-16, (34.45% identity in 270 aa overlap); etc. Caution: equivalent to AAK47636 from Mycobacterium tuberculosis strain CDC1551 (386 aa) but shorter 72 aa. Contains PS00893 mutT domain signature. BELONGS TO THE NUDIX HYDROLASE FAMILY, NUDC SUBFAMILY. COFACTOR: REQUIRES DIVALENT IONS: MANGANESE OR MAGNESIUM. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3526147 | 3527088 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3224c|nudC
MTNVSGVDFQLRSVPLLSRVGADRADRLRTDMEAAAAGWPGAALLRVDSRNRVLVANGRVLLGAAIELADKPPPEAVFLGRVEGGRHVWAVRAALQPIADPDIPAEAVDLRGLGRIMDDTSSQLVSSASALLNWHDNARFSALDGAPTKPARAGWSRVNPITGHEEFPRIDPAVICLVHDGADRAVLARQAAWPERMFSLLAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQPWPFPRSLMVGFHALGDPDEEFSFSDGEIAEAAWFTRDEVRAALAAGDWSSASESKLLLPGSISIARVIIESWAACE
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