Gene Mb3225c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3225c
Gene length1068 bp
IdentifierMb3225c
Location 3527147 bp
Protein summary information
Molecular mass38132.9 Da
Isoelectric point7.7116
Protein length355 amino acids
Orthologs
M. tuberculosis H37RvRv3200c
M. tuberculosis MTBC0mtbc0_003404
Cross-references
InterProIPR003148, IPR013099, IPR016040
UniProtKB/TrEMBLQ7TX13
SWISS-MODELA0A1R3Y3F6
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSMEMBRANE CATION TRANSPORTER
CommentsMb3225c, -, len: 355 aa. Equivalent to Rv3200c,len: 355 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 355 aa overlap). Possible transmembrane cation transporter, similar to many transmembrane proteins and putative potassium channels e.g. Q9XA52|SCGD3.27C PUTATIVE MEMBRANE PROTEIN from Streptomyces coelicolor (365 aa), FASTA scores: opt: 1022, E(): 2.6e-53, (49.85% identity in 325 aa overlap); Q9RRZ3|DR2336 PUTATIVE POTASSIUM CHANNEL from Deinococcus radiodurans (320 aa),FASTA scores: opt: 436, E(): 1e-18, (30.9% identity in 304 aa overlap); O28600|AF1673 PUTATIVE POTASSIUM CHANNEL from Archaeoglobus fulgidus (314 aa), FASTA scores: opt: 363,E(): 2.1e-14, (27.2% identity in 309 aa overlap); Q57604|Y13B_METJAMJ0138.1|MJ0138.1 PUTATIVE POTASSIUM CHANNEL from Methanococcus jannaschii (333 aa), FASTA scores: opt: 356, E(): 5.7e-14, (26.0% identity in 281 aa overlap); P73132|SLL0993 POTASSIUM CHANNEL from Synechocystis sp. strain PCC 6803 (365 aa), FASTA scores: opt: 330, E(): 2.1e-12, (27.8% identity in 324 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS35271473528214-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3225c|Mb3225c
MAGSWRRLRGLDEKLTAQPGYALVGVLRIPQRRASPARVISRRVVVAVVALLLTAGIVYVDRDGYLDAQGDRLTFLDCLYYAAVTLSTTGYGDITPISEFARAINIFVITPLRIAFLILLVGTTLEVLTETSRQAYKIQRWRSRVRNHTVVIGYGTKGKTAVAAMVSDELVPGEIVVVDTDSGVLERAAAAGLVTVHGDATKSDVLRLAGTQHASSIIVATSRDDTAVLVTLTAREIAPKAKIVASIREAENQHLLRQSGADTVVVSSETAGRLLGIATTTPSVVEMIEDLLTPEAGLAVAEREVEQAEVGGSPRHLRDIVLGVVRDGQLLRIGAPEVDAIEASDRLLYIRQVGR
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