Gene Mb3254c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3254c
Gene length1425 bp
IdentifierMb3254c
Location 3555615 bp
Protein summary information
Molecular mass51301.4 Da
Isoelectric point5.2125
Protein length474 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_003434
M. tuberculosis H37RvRv3225c
Cross-references
InterProIPR000182, IPR002575, IPR011009, IPR016181, IPR024165
UniProtKB/TrEMBLQ7TWY6
SWISS-MODELA0A1R3Y3H8
General annotation
TypeCDS
FunctionUnknown
Productgcn5-related n-acetyltransferase, phosphorylase
CommentsMb3254c, -, len: 474 aa. Equivalent to Rv3225c,len: 474 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 474 aa overlap). Possible transferase (EC 2.-.-.-). C-terminal part shows some similarity to various bacterial proteins e.g. BAB49093|MLL1809 HYPOTHETICAL PROTEIN from Rhizobium loti (Mesorhizobium loti) (298 aa), FASTA scores: opt: 557, E(): 2.8e-26,(34.55% identity in 295 aa overlap); P14509|KKA8_ECOLI|APHA AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE from Escherichia coli (271 aa),FASTA scores: opt: 194, E(): 0.00018, (27.75% identity in 227 aa overlap); Q53826|CPH CAPREOMYCIN PHOSPHOTRANSFERASE from Streptomyces capreolus (281 aa), FASTA scores: opt: 178, E(): 0.0017, (30.5% identity in 269 aa overlap); Q9CDM4|YWIA UNKNOWN PROTEIN from Lactococcus lactis (subsp. lactis) (Streptococcus lactis) (213 aa), FASTA scores: opt: 167, E(): 0.0061, (2705% identity in 149 aa overlap); Q9X843|SC9B1.24 PUTATIVE TRANSFERASE (FRAGMENT) from Streptomyces coelicolor (317 aa), FASTA scores: opt: 165, E(): 0.011, (26.05% identity in 280 aa overlap); etc. Start uncertain.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS35556153557039-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3254c|Mb3254c
MRFAKLSDGLSDGIVTLSPLCLDDVDAHLAGGDERLVRWLSGMPSTRASVEAYIRHCREQWVTGGPLRSFGIRTVAETIVGTIDLRFDGEGLASGQVNVAYGLYPSWRGRGLATRAVDLVCQYAAEHGATEAVIKVEPENSASARVALRAGFAFVRRICEQDGTVFDRYERVLRAKMHADEVDIDEDLVRRLLRAQFPQWADLPIAPVRSAGTDNAMYRLGEDLAVRIPRIGWAIESLRTEQQWLPRIAAHLGVASPVPVGLGSPAEGFGWPWSVCRWVAGENPSAAEFVEPNRAVEDLADFITTLRATDPMGGPPAKRGAPLGEQDAEVRAALAALDGIIDVHAATAAWESALRVPPYAGPPMWFHGDLSRFNILTAQGRLTGVIDFGLMGVGDPSVDLIIAWNLLSAPARAQFRVAVGAADDDWMRGRGRALAIALIALPYYQDTNPPLAASARYAIGEVLADFRYGARPGC
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