Gene Mb3256 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namearoA
Gene length1353 bp
IdentifierMb3256
Location 3557976 bp
Protein summary information
Molecular mass46406.8 Da
Isoelectric point8.7588
Protein length450 amino acids
Orthologs
M. tuberculosis H37RvRv3227
M. tuberculosis MTBC0mtbc0_003436
Cross-references
UniProtKB/TrEMBLX2BMZ8, Q7TWY4
SWISS-MODELQ7TWY4
General annotation
TypeCDS
FunctionUnknown
Product3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE AROA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS)
CommentsMb3256, aroA, len: 450 aa. Equivalent to Rv3227,len: 450 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 450 aa overlap). aroA,3-phosphoshikimate 1-carboxyvinyl transferase (EC 2.5.1.19) (see citation below), equivalent (but C-terminus longer) to Q9CCI3|AROA|ML0792 PUTATIVE 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYL TRANSFERASE from Mycobacterium leprae (430 aa), FASTA scores: opt: 1466, E(): 1.4e-78, (55.05% identity in 427 aa overlap). Contains PS00885 EPSP synthase signature 2. BELONGS TO THE EPSP SYNTHASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS35579763559328+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3256|aroA
MKTWPAPTAPTPVRATVTVPGSKSQTNRALVLAALAAAQGRGASTISGALRSRDTELMLDALQTLGLRVDGVGSELTVSGRIEPGPGARVDCGLAGTVLRFVPPLAALGSVPVTFDGDQQARGRPIAPLLDALRELGVAVDGTGLPFRVHGNGSLAGGTVAIDASASSQFVSGLLLSAASFTDGLTVQHTGSSLPSAPHIAMTAAMLRQAGVDIDDSTPNRWQVRPGPVAARRWDIEPDLTNAVAFLSAAVVSGGTVRITGWPRVSVQPADHILAILRQLNAVVIHADSSLEVRGPTGYDGFDVDLRAVGELTPSVAALAALASPGSVSRLSGIAHLRGHETDRLAALSTEINRLGGTCRETPDGLVITATPLRPGIWRAYADHRMAMAGAIIGLRVAGVEVDDIAATTKTLPEFPRLWAEMVGPGQGWGYPQPRSGQRARRATGQGSGG
Bibliography
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