Gene Mb3261c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | polyphosphate kinase ppk2 (polyphosphoric acid kinase) |
| Comments | Mb3261c, pvdS, len: 295 aa. Equivalent to Rv3232c,len: 295 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 295 aa overlap). Possible pvdS, an alternative RNA polymerase sigma factor, highly similar (but N-terminus longer 25-50 residues approximatively) to Q9RIZ9|SCJ1.15 PUTATIVE REGULATOR from Streptomyces coelicolor (267 aa), FASTA scores: opt: 1189, E(): 1.4e-70, (65.65% identity in 262 aa overlap); Q9KU02|VC0728 HYPOTHETICAL PROTEIN from Vibrio cholerae (258 aa), FASTA scores: opt: 1074, E(): 4.5e-63, (62.6% identity in 254 aa overlap); P72119|PVDS PAO SUBSTRAIN OT684 PYOVERDINE GENE TRANSCRIPTIONAL REGULATOR PVDS (FRAGMENT) from Pseudomonas aeruginosa (see citation below) (237 aa), FASTA scores: opt: 988, E(): 1.8e-57,(60.8% identity in 227 aa overlap). Also highly similar to Q9I154|PA2428 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (304 aa), FASTA scores: opt: 1057, E(): 6.8e-62, (60.7% identity in 252 aa overlap); Q9I6Z1|PA0141 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (298 aa),FASTA scores: opt: 990, E(): 1.6e-57, (54.6% identity in 249 aa overlap); and other hypothetical bacterial proteins. Could be a member of a subfamily of RNA polymerase sigma factors which direct the synthesis of extracellular products by bacteria. Start uncertain. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3563469 | 3564356 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3261c|ppk2
MDIPSVDVSTATNDGASSRAKGHRSAAPGRRKISDAVYQAELFRLQTEFVKLQEWARHSGARLVVIFEGRDGAGKGGAIKRITEYLNPRVARIAALPAPTDRERGQWYYQRYIAHLPAKGEIVLFDRSWYNRAGVEKVMGFCTPQEYVLFLRQTPIFEQMLIDDGILLRKYWFSVSDAEQLRRFKARRNDPVRQWKLSPMDLESVYRWEDYSRAKDEMMVHTDTPVSPWYVVESDIKKHARLNMMAHLLSTIDYADVEKPKVKLPPRPLVSGNYRRPPRELSTYVDDYVATLIAR
Bibliography
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