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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN
CommentsMb3264c, -, len: 385 aa. Equivalent to Rv3236c,len: 385 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 385 aa overlap). Probable conserved integral membrane transport protein, possibly cation (Na/H) transporter, equivalent to Q9CCI5|ML0782 putative transmembrane transport protein from Mycobacterium leprae (385 aa), FASTA scores: opt: 1975, E(): 2.4e-108, (81.55% identity in 385 aa overlap). Highly similar to others e.g. O69958|SC4H2.03c putative transmembrane transport protein from Streptomyces coelicolor (411 aa), FASTA scores: opt: 1226, E(): 1.6e-64, (53.5% identity in 372 aa overlap); Q9XAKO|SC66T3.13c putative transmembrane transport protein from Streptomyces coelicolor (403 aa), FASTA scores: opt: 1198, E(): 6.8e-63, (53.25% identity in 370 aa overlap); Q9RV80|DR1149 putative Na+/H+ antiporter from Deinococcus radiodurans (383 aa), FASTA scores: opt: 1069, E(): 2.3e-55, (47.35% identity in 376 aa overlap); Q9L191|SC10G8.11 putative transmembrane transport protein from Streptomyces coelicolor (446 aa), FASTA scores: opt: 695, E(): 1.9e-33, (38.05% identity in 384 aa overlap); Q9RRW8|DR2367 putative glutathione-regulated potassium-efflux system protein KEFB from Deinococcus radiodurans (575 aa), FASTA scores: opt: 414, E(): 6.2e-17, (30.25% identity in 380 aa overlap); etc. SEEMS TO BELONG TO THE CPA2 FAMILY. Note that previously known as kefB.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS35665593567716-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3264c|Mb3264c
MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN
      
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