Gene Mb3273c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | TWO COMPONENT SENSORY TRANSDUCTION HISTIDINE KINASE MTRB |
| Comments | Mb3273c, mtrB, len: 567 aa. Equivalent to Rv3245c,len: 567 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 567 aa overlap). mtrB, sensor-like histidine kinase (EC 2.7.3.-) (see citations below),equivalent to Q9CCJ1|MTRB OR ML0774 PUTATIVE TWO-COMPONENT SYSTEM SENSOR KINASE from Mycobacterium leprae (562 aa),FASTA scores: opt: 3208, E(): 7.4e-173, (88.7% identity in 566 aa overlap). Also similar to others e.g. Q9KYW9|SCE33.14c PUTATIVE TWO-COMPONENT SYSTEM HISTIDINE KINASE from Streptomyces coelicolor (688 aa), FASTA scores: opt: 1355, E(): 1.1e-68, (48.95% identity in 515 aa overlap); etc. Relatives in Mycobacterium tuberculosis are: MTCY369.03, E(): 1.5e-22; MTCY20G9.16, E(): 1.9e-17. SIMILAR TO OTHER PROKARYOTIC SENSORY TRANSDUCTION HISTIDINE KINASES. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3579510 | 3581213 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3273c|mtrB
MIFGSRRRIRGRRGRSGPMTRGLSALSRAVAVAWRRSLQLRVVALTLGLSLAVILALGFVLTSQVTNRVLDIKVRAAIDQIERARTTVSGIVNGEETRSLDSSLQLARNTLTSKTDPASGAGLAGAFDAVLMVPGDGPRAASTAGPVDQVPNALRGFVKAGQAAYQYATVQTEGFSGPALIIGTPTLSRVANLELYLIFPLASEQATITLVRGTMATGGLVLLVLLAGIALLVSRQVVVPVRSASRIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESLSRQIAQLEEFGNLQRRFTSDVSHELRTPLTTVRMAADLIYDHSADLDPTLRRSTELMVSELDRFETLLNDLLEISRHDAGVAELSVEAVDLRTTVNNALGNVGHLAEEAGIELLVDLPAEQVIAEVDARRVERILRNLIANAIDHAEHKPVRIRMAADEDTVAVTVRDYGVGLRPGEEKLVFSRFWRSDPSRVRRSGGTGLGLAISVEDARLHQGRLEAWGEPGEGACFRLTLPLVRGHKVTTSPLPMKPIPQPVLQPVAQPNPQPMPPEYKERQRPREHAEWSG
Bibliography
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