Gene Mb3291 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3291
Gene length1662 bp
IdentifierMb3291
Location 3597777 bp
Protein summary information
Molecular mass60673.5 Da
Isoelectric point8.2285
Protein length553 amino acids
Orthologues
M. tuberculosisRv3263
Cross-references
InterProIPR002052, IPR002296
UniProtKB/TrEMBLQ7TWV2
SWISS-MODELA0A1R3Y3M1
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DNA METHYLASE (MODIFICATION METHYLASE) (METHYLTRANSFERASE)
CommentsMb3291, -, len: 553 aa. Equivalent to Rv3263, len: 553 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 553 aa overlap). Probable DNA methylase (EC 2.1.1.-), equivalent to Q9CCK4|ML0756 PROBABLE DNA METHYLASE from Mycobacterium leprae (555 aa),FASTA scores: opt: 2980, E(): 2.1e-184, (81.9% identity in 541 aa overlap). Also similar to others e.g. P25240|MT57_ECOLI|ECO57IM MODIFICATION METHYLASE from Escherichia coli (544 aa), FASTA scores: opt: 595, E(): 1e-30, (30.35% identity in 507 aa overlap); P25201|MTA1_ACICA|ACCIM MODIFICATION METHYLASE ACCI from Acinetobacter calcoaceticus (540 aa), FASTA scores: opt: 366, E(): 5.7e-16, (23.35% identity in 467 aa overlap); Q56752|M-ACCI ACCI METHYLASE from Bergeyella zoohelcum (541 aa), FASTA scores: opt: 365, E(): 6.6e-16, (22.95% identity in 466 aa overlap); etc. Contains PS00092 N-6 Adenine-specific DNA methylases signature. Alternative start site at aa 25.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS35977773599438+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3291|Mb3291
MQPSHPTRPGAVIRYVGSSLDTCPMTTFAGKTAASADKVRGGYYTPPAVARFLAHWVHQAGPKILEPSCGDGRILRELSAITDHAHGVELVAREAKKSRDFASVDTENLFTWLHKTQLGSWDGVAGNPPYIRFGNWASEQRDPALELMRRVGLRPTKLTNAWVPFVVASTTLARDGGRVGLVVPAELLQVTYAAQLREFLLSRYREITLVTFERLVFDGILQEVVLFCGVVGPGPAHIRTVRLGDANDLNALGDKDFTNESAPALLHEKEKWTKYFLDPAQIRLLRGLKQSATMIRLGELADVDVGIVTGRNSFFTFTDAKAQALGLRAHCVPLVSRSAQLSGLIYDEDCRACDVAGNHRTWLLDAADYPTDPALVAHITAGEAAGVHLGYKCSIRKPWWSTPSLWMPDLFMLRQIHFAPRLTVNAAAATSTDTVHRVRLDPNVDPATLAAVFHNSATFAFAEIMGRSYGGGILELEPREAEQLPMPPPAYGSAELAQDVDLLLKANEIDKALDVVDRHVLIDGLGLSPRLVAGCRAAWLTLRDRRTKRGSRR
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